Zainab Doctor

Harvard University, Cambridge, MA, United States 
cancer biology, kinase inhibitors, cyclin dependent kinases
"Zainab Doctor"
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Koide E, Mohardt ML, Doctor ZM, et al. (2023) Development and characterization of selective FAK inhibitors and PROTACs with in vivo activity. Chembiochem : a European Journal of Chemical Biology. e202300141
Dubiella C, Pinch BJ, Koikawa K, et al. (2021) Sulfopin is a covalent inhibitor of Pin1 that blocks Myc-driven tumors in vivo. Nature Chemical Biology
Pinch BJ, Doctor ZM, Nabet B, et al. (2020) Identification of a potent and selective covalent Pin1 inhibitor. Nature Chemical Biology
Li Z, Pinch BJ, Olson CM, et al. (2019) Development and Characterization of a Wee1 Kinase Degrader. Cell Chemical Biology
Ferguson FM, Doctor ZM, Ficarro SB, et al. (2019) Synthesis and structure activity relationships of a series of 4-amino-1H-pyrazoles as covalent inhibitors of CDK14. Bioorganic & Medicinal Chemistry Letters
Ferguson FM, Doctor ZM, Ficarro SB, et al. (2019) Discovery of Covalent CDK14 Inhibitors with Pan-TAIRE Family Specificity. Cell Chemical Biology
Pinch B, Doctor Z, Browne CM, et al. (2019) Abstract 2757: Discovery and characterization of covalent Pin1 inhibitors targeted to an active site cysteine Cancer Research. 79: 2757-2757
Browne CM, Jiang B, Ficarro SB, et al. (2018) A Chemoproteomic Strategy for Direct and Proteome-wide Covalent Inhibitor Target-site Identification. Journal of the American Chemical Society
Kozono S, Lin YM, Seo HS, et al. (2018) Arsenic targets Pin1 and cooperates with retinoic acid to inhibit cancer-driving pathways and tumor-initiating cells. Nature Communications. 9: 3069
Olson CM, Jiang B, Erb MA, et al. (2017) Pharmacological perturbation of CDK9 using selective CDK9 inhibition or degradation. Nature Chemical Biology
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