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Fleur Marcia Ferguson

Affiliations: 
Harvard Medical School/Dana-Farber Cancer Institute, Boston, MA, United States 
Area:
Chemical Biology
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"Fleur Ferguson"
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Parents

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Christopher Abell grad student 2010-2014 Cambridge
Alessio Ciulli grad student 2010-2014 University of Cambridge, United Kingdom
Nathanael Gray post-doc 2015- Harvard Medical School/Dana-Farber Cancer Institute

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Publications

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Carli ALE, Afshar-Sterle S, Rai A, et al. (2021) Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells. Proteomics. e2000098
Jiang B, Jiang J, Kaltheuner IH, et al. (2021) Structure-activity relationship study of THZ531 derivatives enables the discovery of BSJ-01-175 as a dual CDK12/13 covalent inhibitor with efficacy in Ewing sarcoma. European Journal of Medicinal Chemistry. 221: 113481
Donovan KA, Ferguson FM, Bushman JW, et al. (2020) Mapping the Degradable Kinome Provides a Resource for Expedited Degrader Development. Cell
Nabet B, Ferguson FM, Seong BKA, et al. (2020) Rapid and direct control of target protein levels with VHL-recruiting dTAG molecules. Nature Communications. 11: 4687
Ferguson FM, Liu Y, Harshbarger W, et al. (2020) Correction to "Synthesis and Structure-Activity Relationships of DCLK1 Kinase Inhibitors Based on a 5,11-Dihydro-6-benzo[]pyrimido[5,4-][1,4]diazepin-6-one Scaffold". Journal of Medicinal Chemistry
Liu Y, Ferguson FM, Li L, et al. (2020) Chemical Biology Toolkit for DCLK1 Reveals Connection to RNA Processing. Cell Chemical Biology
Ferguson FM, Liu Y, Harshbarger W, et al. (2020) Synthesis and structure activity relationships of DCLK1 kinase inhibitors based on a 5,11-dihydro-6H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6-one scaffold. Journal of Medicinal Chemistry
Jaeger MG, Schwalb B, Mackowiak SD, et al. (2020) Selective Mediator dependence of cell-type-specifying transcription. Nature Genetics
Manz TD, Sivakumaren SC, Ferguson FM, et al. (2020) Discovery and Structure-Activity Relationship Study of (Z)-5-Methylenethiazolidin-4-one Derivatives as Potent and Selective Pan-phosphatidylinositol 5-Phosphate 4-Kinase Inhibitors. Journal of Medicinal Chemistry
Ferguson FM, Nabet B, Raghavan S, et al. (2020) Discovery of a selective inhibitor of doublecortin like kinase 1. Nature Chemical Biology
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