Fleur M. Ferguson
Affiliations: | University of California, San Diego, La Jolla, CA |
Area:
Chemical BiologyGoogle:
"Fleur Ferguson"Mean distance: (not calculated yet)
Parents
Sign in to add mentorAlan C. Spivey | research assistant | 2009-2010 | Imperial College London |
Christopher Abell | grad student | 2010-2014 | Cambridge |
Alessio Ciulli | grad student | 2010-2014 | University of Cambridge, United Kingdom |
Nathanael Gray | post-doc | 2015- | Harvard Medical School/Dana-Farber Cancer Institute |
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Publications
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Tran NL, Leconte GA, Ferguson FM. (2022) Targeted Protein Degradation: Design Considerations for PROTAC Development. Current Protocols. 2: e611 |
Silva MC, Nandi G, Donovan KA, et al. (2022) Discovery and Optimization of Tau Targeted Protein Degraders Enabled by Patient Induced Pluripotent Stem Cells-Derived Neuronal Models of Tauopathy. Frontiers in Cellular Neuroscience. 16: 801179 |
Tao AJ, Gadbois GE, Buczynski SA, et al. (2022) Targeted protein degradation: Emerging concepts and protein state-specific targeting principles. Current Opinion in Chemical Biology. 67: 102114 |
Seong BKA, Dharia NV, Lin S, et al. (2021) TRIM8 modulates the EWS/FLI oncoprotein to promote survival in Ewing sarcoma. Cancer Cell |
Carli ALE, Afshar-Sterle S, Rai A, et al. (2021) Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells. Proteomics. e2000098 |
Jiang B, Jiang J, Kaltheuner IH, et al. (2021) Structure-activity relationship study of THZ531 derivatives enables the discovery of BSJ-01-175 as a dual CDK12/13 covalent inhibitor with efficacy in Ewing sarcoma. European Journal of Medicinal Chemistry. 221: 113481 |
Donovan KA, Ferguson FM, Bushman JW, et al. (2020) Mapping the Degradable Kinome Provides a Resource for Expedited Degrader Development. Cell |
Nabet B, Ferguson FM, Seong BKA, et al. (2020) Rapid and direct control of target protein levels with VHL-recruiting dTAG molecules. Nature Communications. 11: 4687 |
Ferguson FM, Liu Y, Harshbarger W, et al. (2020) Correction to "Synthesis and Structure-Activity Relationships of DCLK1 Kinase Inhibitors Based on a 5,11-Dihydro-6-benzo[]pyrimido[5,4-][1,4]diazepin-6-one Scaffold". Journal of Medicinal Chemistry |
Liu Y, Ferguson FM, Li L, et al. (2020) Chemical Biology Toolkit for DCLK1 Reveals Connection to RNA Processing. Cell Chemical Biology |