Fleur M. Ferguson

University of California, San Diego, La Jolla, CA 
Chemical Biology
"Fleur Ferguson"
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Tao AJ, Jiang J, Gadbois GE, et al. (2023) A biotin targeting chimera (BioTAC) system to map small molecule interactomes in situ. Nature Communications. 14: 8016
Tao AJ, Jiang J, Gadbois GE, et al. (2023) A Biotin Targeting Chimera (BioTAC) System to Map Small Molecule Interactomes . Biorxiv : the Preprint Server For Biology
Fan AT, Boyle BT, Ferguson FM. (2023) A new avenue for molecular glues: Rapid discovery of a NFKB1 degrader. Cell Chemical Biology. 30: 340-342
Tran NL, Leconte GA, Ferguson FM. (2022) Targeted Protein Degradation: Design Considerations for PROTAC Development. Current Protocols. 2: e611
Silva MC, Nandi G, Donovan KA, et al. (2022) Discovery and Optimization of Tau Targeted Protein Degraders Enabled by Patient Induced Pluripotent Stem Cells-Derived Neuronal Models of Tauopathy. Frontiers in Cellular Neuroscience. 16: 801179
Tao AJ, Gadbois GE, Buczynski SA, et al. (2022) Targeted protein degradation: Emerging concepts and protein state-specific targeting principles. Current Opinion in Chemical Biology. 67: 102114
Seong BKA, Dharia NV, Lin S, et al. (2021) TRIM8 modulates the EWS/FLI oncoprotein to promote survival in Ewing sarcoma. Cancer Cell
Carli ALE, Afshar-Sterle S, Rai A, et al. (2021) Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells. Proteomics. e2000098
Jiang B, Jiang J, Kaltheuner IH, et al. (2021) Structure-activity relationship study of THZ531 derivatives enables the discovery of BSJ-01-175 as a dual CDK12/13 covalent inhibitor with efficacy in Ewing sarcoma. European Journal of Medicinal Chemistry. 221: 113481
Donovan KA, Ferguson FM, Bushman JW, et al. (2020) Mapping the Degradable Kinome Provides a Resource for Expedited Degrader Development. Cell
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