Yao Liu

Dana-Farber Cancer Institute and Harvard Medical School, USA 
cancer research
"Yao Liu"
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Chen M, Yin B, Liu Y, et al. (2024) ARRDC3 regulates the targeted therapy sensitivity of clear cell renal cell carcinoma by promoting AXL degradation. Cell Cycle (Georgetown, Tex.). 1-14
Song Y, Malpica L, Cai Q, et al. (2023) Golidocitinib, a selective JAK1 tyrosine-kinase inhibitor, in patients with refractory or relapsed peripheral T-cell lymphoma (JACKPOT8 Part B): a single-arm, multinational, phase 2 study. The Lancet. Oncology
Arwood ML, Liu Y, Harkins SK, et al. (2023) New scaffolds for type II JAK2 inhibitors overcome the acquired G993A resistance mutation. Cell Chemical Biology
Wang K, Lu H, Wang X, et al. (2023) Simultaneous suppression of PKM2 and PHGDH elicits synergistic anti-cancer effect in NSCLC. Frontiers in Pharmacology. 14: 1200538
Lu W, Liu Y, Gao Y, et al. (2023) Development of a Covalent Inhibitor of c-Jun N-Terminal Protein Kinase (JNK) 2/3 with Selectivity over JNK1. Journal of Medicinal Chemistry. 66: 3356-3371
Fan M, Lu W, Che J, et al. (2022) Covalent disruptor of YAP-TEAD association suppresses defective hippo signaling. Elife. 11
Zhang S, Peng X, Li X, et al. (2021) BKM120 sensitizes glioblastoma to the PARP inhibitor rucaparib by suppressing homologous recombination repair. Cell Death & Disease. 12: 546
Jiang T, Wang G, Liu Y, et al. (2021) Development of small-molecule tropomyosin receptor kinase (TRK) inhibitors for fusion cancers. Acta Pharmaceutica Sinica. B. 11: 355-372
Liu Y, Hao M, Leggett A, et al. (2020) Discovery of MFH290: A Potent and Highly Selective Covalent Inhibitor for Cyclin-Dependent Kinase 12/13. Journal of Medicinal Chemistry
Wang G, Zhao Y, Liu Y, et al. (2020) Discovery of a novel dual-target inhibitor of ERK1 and ERK5 that induces regulated cell death to overcome compensatory mechanism in specific tumor types. Journal of Medicinal Chemistry
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