Chelsea E. Powell

Harvard University, Cambridge, MA, United States 
Chemical Biology
"Chelsea Powell"
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Powell CE, Hatcher JM, Jiang J, et al. (2022) Selective Macrocyclic Inhibitors of DYRK1A/B. Acs Medicinal Chemistry Letters. 13: 577-585
Powell CE, Du G, Bushman JW, et al. (2021) Selective degradation-inducing probes for studying cereblon (CRBN) biology. Rsc Medicinal Chemistry. 12: 1381-1390
Adhikari AA, Ramachandran D, Chaudhari SN, et al. (2021) A Gut-Restricted Lithocholic Acid Analog as an Inhibitor of Gut Bacterial Bile Salt Hydrolases. Acs Chemical Biology
Powell CE, Du G, Che J, et al. (2020) Selective Degradation of GSPT1 by Cereblon Modulators Identified via a Focused Combinatorial Library. Acs Chemical Biology
Li Z, Powell CE, Groendyke BJ, et al. (2020) Discovery of a Series of Benzopyrimidodiazepinone TNK2 Inhibitors via Scaffold Morphing. Bioorganic & Medicinal Chemistry Letters. 127456
Groendyke BJ, Powell CE, Feru F, et al. (2020) Benzopyrimidodiazepinone inhibitors of TNK2. Bioorganic & Medicinal Chemistry Letters. 126948
Powell CE, Gao Y, Tan L, et al. (2018) Chemically Induced Degradation of Anaplastic Lymphoma Kinase (ALK). Journal of Medicinal Chemistry
Hatcher JM, Wu G, Zeng C, et al. (2018) SRPKIN-1: A Covalent SRPK1/2 Inhibitor that Potently Converts VEGF from Pro-angiogenic to Anti-angiogenic Isoform. Cell Chemical Biology
POWELL CE, SWANSON EE, CHEN KK. (1955) The pharmacologic action of indole compounds. Journal of the American Pharmaceutical Association. American Pharmaceutical Association. 44: 399-404
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