Guangyan Du

Dana Farber Cancer Institute, Boston, MA, United States 
"Guangyan Du"
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Li Z, Liu HY, He Z, et al. (2024) Discovery of Potent Degraders of the Dengue Virus Envelope Protein. Biorxiv : the Preprint Server For Biology
Zerfas BL, Huerta F, Liu H, et al. (2022) Advancing targeted protein degrader discovery by measuring cereblon engagement in cells. Methods in Enzymology. 681: 169-188
Du G, Jiang J, Henning NJ, et al. (2022) Exploring the target scope of KEAP1 E3 ligase-based PROTACs. Cell Chemical Biology
Powell CE, Du G, Bushman JW, et al. (2021) Selective degradation-inducing probes for studying cereblon (CRBN) biology. Rsc Medicinal Chemistry. 12: 1381-1390
Du G, Jiang J, Wu Q, et al. (2021) Discovery of a Potent Degrader for Fibroblast Growth Factor Receptor 1/2. Angewandte Chemie (International Ed. in English)
Powell CE, Du G, Che J, et al. (2020) Selective Degradation of GSPT1 by Cereblon Modulators Identified via a Focused Combinatorial Library. Acs Chemical Biology
Gurbani D, Du G, Henning NJ, et al. (2020) Structure and Characterization of a Covalent Inhibitor of Src Kinase. Frontiers in Molecular Biosciences. 7: 81
Xiao H, Jedrychowski MP, Schweppe DK, et al. (2020) A Quantitative Tissue-Specific Landscape of Protein Redox Regulation during Aging. Cell
Du G, Rao S, Gurbani D, et al. (2020) Structure-based design of a potent and selective covalent inhibitor for SRC kinase that targets a p-Loop cysteine. Journal of Medicinal Chemistry
de Wispelaere M, Du G, Donovan KA, et al. (2019) Small molecule degraders of the hepatitis C virus protease reduce susceptibility to resistance mutations. Nature Communications. 10: 3468
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