Benika J. Pinch

Harvard University, Cambridge, MA, United States 
chemical biology
"Benika Pinch"
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Schröder M, Renatus M, Liang X, et al. (2024) DCAF1-based PROTACs with activity against clinically validated targets overcoming intrinsic- and acquired-degrader resistance. Nature Communications. 15: 275
Koikawa K, Kibe S, Suizu F, et al. (2021) Targeting Pin1 renders pancreatic cancer eradicable by synergizing with immunochemotherapy. Cell
Dubiella C, Pinch BJ, Koikawa K, et al. (2021) Sulfopin is a covalent inhibitor of Pin1 that blocks Myc-driven tumors in vivo. Nature Chemical Biology
Pinch BJ, Doctor ZM, Nabet B, et al. (2020) Identification of a potent and selective covalent Pin1 inhibitor. Nature Chemical Biology
Li Z, Pinch BJ, Olson CM, et al. (2019) Development and Characterization of a Wee1 Kinase Degrader. Cell Chemical Biology
Pinch B, Doctor Z, Browne CM, et al. (2019) Abstract 2757: Discovery and characterization of covalent Pin1 inhibitors targeted to an active site cysteine Cancer Research. 79: 2757-2757
Kozono S, Lin YM, Seo HS, et al. (2018) Arsenic targets Pin1 and cooperates with retinoic acid to inhibit cancer-driving pathways and tumor-initiating cells. Nature Communications. 9: 3069
Woll KA, Murlidaran S, Pinch BJ, et al. (2016) A Novel Bifunctional Alkylphenol Anesthetic Allows Characterization of GABAA Receptor Subunit Binding Selectivity in Synaptosomes. The Journal of Biological Chemistry
Woll KA, Weiser BP, Liang Q, et al. (2015) Role for the Propofol Hydroxyl in Anesthetic Protein Target Molecular Recognition. Acs Chemical Neuroscience. 6: 927-35
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