Xianming DENG
Affiliations: | School of Life Sciences, Xiamen University |
Area:
Chemical Biology and Medicinal ChemistryGoogle:
"Xianming DENG"Mean distance: (not calculated yet)
Parents
Sign in to add mentorYong Tang | grad student | 2001-2006 | Shanghai Institute of Organic Chemistry(SIOC) |
Nathanael Gray | post-doc | 2006-2012 | Harvard Medical School, Dana Farber Cancer Institute |
Children
Sign in to add traineeWei Huang | grad student | 2013- | School of Life Sciences, Xiamen University |
Shang Han | grad student | 2012-2015 | School of Life Sciences, Xiamen University |
Xiaoxing Huang | grad student | 2011-2016 | School of Life Sciences, Xiamen University |
Fu Gui | grad student | 2012-2016 | School of Life Sciences, Xiamen University |
Jie Jiang | grad student | 2012-2016 | School of Life Sciences, Xiamen University |
Zhixiang He | grad student | 2013-2016 | School of Life Sciences, Xiamen University |
Yan Liu | grad student | 2013-2016 | School of Life Sciences, Xiamen University |
Zhongji Zhuang | grad student | 2013-2016 | School of Life Sciences, Xiamen University |
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Publications
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Li L, Wang Y, Wang Y, et al. (2024) Dimeric natural product panepocyclinol A inhibits STAT3 di-covalent modification. Acta Pharmaceutica Sinica. B. 15: 409-423 |
Bohmer MJ, Wang J, Istvan ES, et al. (2023) Human Polo-like Kinase Inhibitors as Antiplasmodials. Acs Infectious Diseases |
Zhang CS, Li M, Wang Y, et al. (2022) The aldolase inhibitor aldometanib mimics glucose starvation to activate lysosomal AMPK. Nature Metabolism |
Lu Y, Fan Z, Zhu SJ, et al. (2021) A new ALK inhibitor overcomes resistance to first- and second-generation inhibitors in NSCLC. Embo Molecular Medicine. e14296 |
Li X, Su J, Yang Y, et al. (2020) Discovery of 4-methyl-N-(4-((4-methylpiperazin- 1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((6-(pyridin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-oxy)benzamide as a potent inhibitor of RET and its gatekeeper mutant. European Journal of Medicinal Chemistry. 207: 112755 |
Deng Z, Chen G, Liu S, et al. (2020) Discovery of methyl 3-((2-((1-(dimethylglycyl)-5-methoxyindolin-6-yl)amino)-5-(trifluoro-methyl) pyrimidin-4-yl)amino)thiophene-2-carboxylate as a potent and selective polo-like kinase 1 (PLK1) inhibitor for combating hepatocellular carcinoma. European Journal of Medicinal Chemistry. 206: 112697 |
Ferguson FM, Liu Y, Harshbarger W, et al. (2020) Correction to "Synthesis and Structure-Activity Relationships of DCLK1 Kinase Inhibitors Based on a 5,11-Dihydro-6-benzo[]pyrimido[5,4-][1,4]diazepin-6-one Scaffold". Journal of Medicinal Chemistry |
Wang Y, Zhang L, Wei Y, et al. (2020) Pharmacological Targeting of Vacuolar H-ATPase via Subunit V1G Combats Multidrug-Resistant Cancer. Cell Chemical Biology |
Ferguson FM, Liu Y, Harshbarger W, et al. (2020) Synthesis and structure activity relationships of DCLK1 kinase inhibitors based on a 5,11-dihydro-6H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6-one scaffold. Journal of Medicinal Chemistry |
Zhang L, Wang Y, Huang W, et al. (2020) Biosynthesis and Chemical Diversification of Verucopeptin Leads to Structural and Functional Versatility. Organic Letters |