Xianming DENG

Affiliations: 
School of Life Sciences, Xiamen University 
Area:
Chemical Biology and Medicinal Chemistry
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"Xianming DENG"
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Publications

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Bohmer MJ, Wang J, Istvan ES, et al. (2023) Human Polo-like Kinase Inhibitors as Antiplasmodials. Acs Infectious Diseases
Bhuiyan MIH, Fischer S, Patel SM, et al. (2022) Efficacy of novel SPAK inhibitor ZT-1a derivatives (1c, 1d, 1g & 1h) on improving post-stroke neurological outcome and brain lesion in mice. Neurochemistry International. 105441
Zhang CS, Li M, Wang Y, et al. (2022) The aldolase inhibitor aldometanib mimics glucose starvation to activate lysosomal AMPK. Nature Metabolism
Wang J, Liu R, Hasan MN, et al. (2022) Role of SPAK-NKCC1 signaling cascade in the choroid plexus blood-CSF barrier damage after stroke. Journal of Neuroinflammation. 19: 91
Bhuiyan MIH, Young CB, Jahan I, et al. (2022) NF-κB Signaling-Mediated Activation of WNK-SPAK-NKCC1 Cascade in Worsened Stroke Outcomes of Ang II-Hypertensive Mice. Stroke. STROKEAHA121038351
Lu Y, Fan Z, Zhu SJ, et al. (2021) A new ALK inhibitor overcomes resistance to first- and second-generation inhibitors in NSCLC. Embo Molecular Medicine. e14296
Li X, Su J, Yang Y, et al. (2020) Discovery of 4-methyl-N-(4-((4-methylpiperazin- 1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((6-(pyridin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-oxy)benzamide as a potent inhibitor of RET and its gatekeeper mutant. European Journal of Medicinal Chemistry. 207: 112755
Deng Z, Chen G, Liu S, et al. (2020) Discovery of methyl 3-((2-((1-(dimethylglycyl)-5-methoxyindolin-6-yl)amino)-5-(trifluoro-methyl) pyrimidin-4-yl)amino)thiophene-2-carboxylate as a potent and selective polo-like kinase 1 (PLK1) inhibitor for combating hepatocellular carcinoma. European Journal of Medicinal Chemistry. 206: 112697
Ferguson FM, Liu Y, Harshbarger W, et al. (2020) Correction to "Synthesis and Structure-Activity Relationships of DCLK1 Kinase Inhibitors Based on a 5,11-Dihydro-6-benzo[]pyrimido[5,4-][1,4]diazepin-6-one Scaffold". Journal of Medicinal Chemistry
Wang Y, Zhang L, Wei Y, et al. (2020) Pharmacological Targeting of Vacuolar H-ATPase via Subunit V1G Combats Multidrug-Resistant Cancer. Cell Chemical Biology
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