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Xianming DENG

Affiliations: 
School of Life Sciences, Xiamen University 
Area:
Chemical Biology and Medicinal Chemistry
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"Xianming DENG"
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Parents

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Nathanael Gray post-doc 2006-2012 Harvard Medical School, Dana Farber Cancer Institute

Children

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Wei Huang grad student 2013- School of Life Sciences, Xiamen University
Shang Han grad student 2012-2015 School of Life Sciences, Xiamen University
Xiaoxing Huang grad student 2011-2016 School of Life Sciences, Xiamen University
Fu Gui grad student 2012-2016 School of Life Sciences, Xiamen University
Jie Jiang grad student 2012-2016 School of Life Sciences, Xiamen University
Zhixiang He grad student 2013-2016 School of Life Sciences, Xiamen University
Yan Liu grad student 2013-2016 School of Life Sciences, Xiamen University
Zhongji Zhuang grad student 2013-2016 School of Life Sciences, Xiamen University

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Publications

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Yang PB, Hou PP, Liu FY, et al. (2020) Blocking PPARγ interaction facilitates Nur77 interdiction of fatty acid uptake and suppresses breast cancer progression. Proceedings of the National Academy of Sciences of the United States of America
Li X, Su J, Yang Y, et al. (2020) Discovery of 4-methyl-N-(4-((4-methylpiperazin- 1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((6-(pyridin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-oxy)benzamide as a potent inhibitor of RET and its gatekeeper mutant. European Journal of Medicinal Chemistry. 207: 112755
Deng Z, Chen G, Liu S, et al. (2020) Discovery of methyl 3-((2-((1-(dimethylglycyl)-5-methoxyindolin-6-yl)amino)-5-(trifluoro-methyl) pyrimidin-4-yl)amino)thiophene-2-carboxylate as a potent and selective polo-like kinase 1 (PLK1) inhibitor for combating hepatocellular carcinoma. European Journal of Medicinal Chemistry. 206: 112697
Ferguson FM, Liu Y, Harshbarger W, et al. (2020) Correction to "Synthesis and Structure-Activity Relationships of DCLK1 Kinase Inhibitors Based on a 5,11-Dihydro-6-benzo[]pyrimido[5,4-][1,4]diazepin-6-one Scaffold". Journal of Medicinal Chemistry
Li Y, Liu Z, Li L, et al. (2020) Tandem-Mass-Tag Based Proteomic Analysis Facilitates Analyzing Critical Factors of Porous Silicon Nanoparticles in Determining Their Biological Responses under Diseased Condition. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). 7: 2001129
Wang Y, Zhang L, Wei Y, et al. (2020) Pharmacological Targeting of Vacuolar H-ATPase via Subunit V1G Combats Multidrug-Resistant Cancer. Cell Chemical Biology
Ferguson FM, Liu Y, Harshbarger W, et al. (2020) Synthesis and structure activity relationships of DCLK1 kinase inhibitors based on a 5,11-dihydro-6H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6-one scaffold. Journal of Medicinal Chemistry
Zhang L, Wang Y, Huang W, et al. (2020) Biosynthesis and Chemical Diversification of Verucopeptin Leads to Structural and Functional Versatility. Organic Letters
Li W, Ni H, Wu S, et al. (2020) Targeting RIPK3 oligomerization blocks necroptosis without inducing apoptosis. Febs Letters
Tao C, Seyfried WE, Lowell RP, et al. (2020) Deep high-temperature hydrothermal circulation in a detachment faulting system on the ultra-slow spreading ridge. Nature Communications. 11: 1300
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