Baishan Jiang, Ph.D
Affiliations: | 2015- | Harvard Medical School/Dana-Farber Cancer Institute, Boston, MA, United States |
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| Gui F, Jiang B, Jiang J, et al. (2025) Acute BRCAness induction and AR pathway blockage through CDK12/7/9 degradation enhances PARP inhibitor sensitivity in prostate cancer. Science Advances. 11: eadu0847 |
| Jiang B, Chen L, Huang L, et al. (2025) Selective and Potent Molecular Glue Degraders for NIMA-related Kinase 7. Angewandte Chemie (International Ed. in English). e202500169 |
| Huang L, Chen L, Chen L, et al. (2024) Development of Oral, Potent, and Selective CK1α Degraders for AML Therapy. Jacs Au. 4: 4423-4434 |
| Gui F, Jiang B, Jiang J, et al. (2024) Acute BRCAness Induction and AR Signaling Blockage through CDK12/7/9 Degradation Enhances PARP Inhibitor Sensitivity in Prostate Cancer. Biorxiv : the Preprint Server For Biology |
| Ye M, Fang Y, Chen L, et al. (2024) Therapeutic targeting nudix hydrolase 1 creates a MYC-driven metabolic vulnerability. Nature Communications. 15: 2377 |
| Kumarasamy V, Gao Z, Zhao B, et al. (2023) PROTAC-mediated CDK degradation differentially impacts cancer cell cycles due to heterogeneity in kinase dependencies. British Journal of Cancer |
| Koide E, Mohardt ML, Doctor ZM, et al. (2023) Development and characterization of selective FAK inhibitors and PROTACs with in vivo activity. Chembiochem : a European Journal of Chemical Biology. e202300141 |
| Gao Y, Jiang B, Kim H, et al. (2023) Catalytic Degraders Effectively Address Kinase Site Mutations in EML4-ALK Oncogenic Fusions. Journal of Medicinal Chemistry |
| Jiang B, Weinstock DM, Donovan KA, et al. (2023) ITK degradation to block T cell receptor signaling and overcome therapeutic resistance in T cell lymphomas. Cell Chemical Biology. 30: 383-393.e6 |
| Gao X, Wu Y, Chick JM, et al. (2023) Targeting protein tyrosine phosphatases for CDK6-induced immunotherapy resistance. Cell Reports. 42: 112314 |