Dustin McMinn

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1998-1999 Scripps Research Institute, La Jolla, La Jolla, CA, United States 
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"Dustin McMinn"
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Sun D, Ye Q, Yan X, et al. (2014) Synthesis, in Vitro Covalent Binding Evaluation, and Metabolism of (14)C-Labeled Inhibitors of 11β-HSD1. Acs Medicinal Chemistry Letters. 5: 1245-50
Yu M, Wang Y, Zhu J, et al. (2014) Discovery of Potent and Simplified Piperidinone-Based Inhibitors of the MDM2-p53 Interaction. Acs Medicinal Chemistry Letters. 5: 894-9
Fox BM, Sugimoto K, Iio K, et al. (2014) Discovery of 6-phenylpyrimido[4,5-b][1,4]oxazines as potent and selective acyl CoA:diacylglycerol acyltransferase 1 (DGAT1) inhibitors with in vivo efficacy in rodents. Journal of Medicinal Chemistry. 57: 3464-83
Li Z, Wang X, Eksterowicz J, et al. (2014) Discovery of AMG 925, a FLT3 and CDK4 dual kinase inhibitor with preferential affinity for the activated state of FLT3. Journal of Medicinal Chemistry. 57: 3430-49
Gonzalez AZ, Eksterowicz J, Bartberger MD, et al. (2014) Selective and potent morpholinone inhibitors of the MDM2-p53 protein-protein interaction. Journal of Medicinal Chemistry. 57: 2472-88
Shin Y, Bergeron P, Fox BM, et al. (2014) A Practical Synthesis of a Potent and Selective Diacylglycerol Acyltransferase-1 (DGAT-1) Inhibitor Synthesis
Gonzalez-Lopez de Turiso F, Sun D, Rew Y, et al. (2013) Rational design and binding mode duality of MDM2-p53 inhibitors. Journal of Medicinal Chemistry. 56: 4053-70
Rew Y, DeGraffenreid M, He X, et al. (2012) Discovery and optimization of benzenesulfonanilide derivatives as a novel class of 11β-HSD1 inhibitors. Bioorganic & Medicinal Chemistry Letters. 22: 3786-90
Brown ML, Aaron W, Austin RJ, et al. (2011) Discovery of amide replacements that improve activity and metabolic stability of a bis-amide smoothened antagonist hit. Bioorganic & Medicinal Chemistry Letters. 21: 5206-9
Sun D, Wang Z, Caille S, et al. (2011) Synthesis and optimization of novel 4,4-disubstituted cyclohexylbenzamide derivatives as potent 11β-HSD1 inhibitors. Bioorganic & Medicinal Chemistry Letters. 21: 405-10
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