Derek Cogan
Affiliations: | 1999 | Boehringer Ingelheim |
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| Meyers K, Cogan DA, Burke J, et al. (2017) Dihydrobenzisoxazole-4-one compounds are novel selective inhibitors of aldosterone synthase (CYP11B2) with in vivo activity. Bioorganic & Medicinal Chemistry Letters |
| Abeywardane A, Caviness G, Choi Y, et al. (2016) N-Arylsulfonyl-α-amino carboxamides are potent and selective inhibitors of the chemokine receptor CCR10 that show efficacy in the murine DNFB model of contact hypersensitivity. Bioorganic & Medicinal Chemistry Letters |
| Weldon SM, Cerny MA, Gueneva-Boucheva K, et al. (2016) Selectivity of BI 689648 - A Novel, Highly Selective Aldosterone Synthase Inhibitor: Comparison to FAD286 and LCI699 in Non-Human Primates. The Journal of Pharmacology and Experimental Therapeutics |
| Moss N, Xiong Z, Burke M, et al. (2012) Exploration of cathepsin S inhibitors characterized by a triazole P1-P2 amide replacement. Bioorganic & Medicinal Chemistry Letters. 22: 7189-93 |
| Boyer SJ, Burke J, Guo X, et al. (2012) Indole RSK inhibitors. Part 1: discovery and initial SAR. Bioorganic & Medicinal Chemistry Letters. 22: 733-7 |
| Moss N, Choi Y, Cogan D, et al. (2009) A new class of 5-HT2B antagonists possesses favorable potency, selectivity, and rat pharmacokinetic properties. Bioorganic & Medicinal Chemistry Letters. 19: 2206-10 |
| Xiong Z, Gao DA, Cogan DA, et al. (2008) Synthesis and SAR studies of indole-based MK2 inhibitors. Bioorganic & Medicinal Chemistry Letters. 18: 1994-9 |
| Goldberg DR, Choi Y, Cogan D, et al. (2008) Pyrazinoindolone inhibitors of MAPKAP-K2. Bioorganic & Medicinal Chemistry Letters. 18: 938-41 |
| Cywin CL, Dahmann G, Prokopowicz AS, et al. (2007) Discovery of potent and selective PKC-theta inhibitors. Bioorganic & Medicinal Chemistry Letters. 17: 225-30 |