Justin Anglin
Affiliations: | Calibr |
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Modukuri RK, Yu Z, Tan Z, et al. (2022) Discovery of potent BET bromodomain 1 stereoselective inhibitors using DNA-encoded chemical library selections. Proceedings of the National Academy of Sciences of the United States of America. 119: e2122506119 |
Taylor DM, Anglin J, Hu L, et al. (2021) Unique Diacidic Fragments Inhibit the OXA-48 Carbapenemase and Enhance the Killing of Producing OXA-48. Acs Infectious Diseases |
Yu Z, Ku AF, Anglin JL, et al. (2021) Discovery and characterization of bromodomain 2-specific inhibitors of BRDT. Proceedings of the National Academy of Sciences of the United States of America. 118 |
Lucki NC, Villa GR, Vergani N, et al. (2019) A cell type-selective apoptosis-inducing small molecule for the treatment of brain cancer. Proceedings of the National Academy of Sciences of the United States of America |
Holt MC, Assar Z, Beheshti Zavareh R, et al. (2018) Biochemical Characterization and Structure-based Mutational Analysis Provides Insight into Binding and Mechanism of Action of Novel Aspartate Aminotransferase Inhibitors. Biochemistry |
Anglin J, Zavareh RB, Sander PN, et al. (2018) Discovery and optimization of aspartate aminotransferase 1 inhibitors to target redox balance in pancreatic ductal adenocarcinoma. Bioorganic & Medicinal Chemistry Letters |
Lum KM, Sato Y, Beyer BA, et al. (2017) Mapping Protein Targets of Bioactive Small Molecules Using Lipid-Based Chemical Proteomics. Acs Chemical Biology |
Mullarky E, Lucki NC, Beheshti Zavareh R, et al. (2016) Identification of a small molecule inhibitor of 3-phosphoglycerate dehydrogenase to target serine biosynthesis in cancers. Proceedings of the National Academy of Sciences of the United States of America |
Anglin JL, Song Y. (2013) A medicinal chemistry perspective for targeting histone H3 lysine-79 methyltransferase DOT1L. Journal of Medicinal Chemistry. 56: 8972-83 |
Zheng B, Yao Y, Liu Z, et al. (2013) Crystallographic Investigation and Selective Inhibition of Mutant Isocitrate Dehydrogenase. Acs Medicinal Chemistry Letters. 4: 542-546 |