Gary L. Johnson, Ph.D.

Affiliations: 
Pharmacology University of Colorado, Boulder, Boulder, CO, United States 
Website:
http://www.med.unc.edu/pharm/people/primaryfaculty/gary-l-johnson
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Publications

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Gomez SM, Drewry DH, Willson TM, et al. (2024) Illuminating function of the understudied druggable kinome. Drug Discovery Today. 103881
Joisa CU, Chen KA, Beville S, et al. (2023) Combined kinome inhibition states are predictive of cancer cell line sensitivity to kinase inhibitor combination therapies. Biorxiv : the Preprint Server For Biology
Asquith CRM, Temme L, East MP, et al. (2022) Identification of 4-anilino-quin(az)oline as a cell active Protein Kinase Novel 3 (PKN3) inhibitor chemotype. Chemmedchem
East MP, Johnson GL. (2021) Adaptive chromatin remodeling and transcriptional changes of the functional kinome in tumor cells in response to targeted kinase inhibition. The Journal of Biological Chemistry. 101525
Pucciarelli D, Angus SP, Huang B, et al. (2020) Nf1 mutant tumors undergo transcriptome and kinome re-modeling after inhibition of either mTOR or MEK. Molecular Cancer Therapeutics
Goulet DR, Foster JP, Zawistowski JS, et al. (2020) Discrete Adaptive Responses to MEK Inhibitor in Subpopulations of Triple-Negative Breast Cancer. Molecular Cancer Research : McR
Garcia-Recio S, Thennavan A, East MP, et al. (2020) FGFR4 regulates tumor subtype differentiation in luminal breast cancer and metastatic disease. The Journal of Clinical Investigation
Lipner MB, Peng XL, Jin C, et al. (2020) Irreversible JNK1-JUN inhibition by JNK-IN-8 sensitizes pancreatic cancer to 5-FU/FOLFOX chemotherapy. Jci Insight
Yesilkanal AE, Yang D, Tiwari P, et al. (2020) Abstract 5038: Limited inhibition of multiple nodes in a driver network blocks metastasis Cancer Research. 80: 5038-5038
Park SI, Lin CP, Ren N, et al. (2019) Inhibition of Aurora A Kinase in Combination with Chemotherapy Induces Synthetic Lethality and Overcomes Chemoresistance in Myc-Overexpressing Lymphoma. Targeted Oncology
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