Arthur L. Horwich

Affiliations: 
Genetics and Pediatrics Yale University, New Haven, CT 
Area:
chaperonins
Website:
http://medicine.yale.edu/labs/horwich/www/
Google:
"Arthur Horwich"
Bio:

http://www.nasonline.org/member-directory/members/2540934.html
http://news.yale.edu/2011/09/12/yales-horwich-wins-lasker-award-one-sciences-top-honors

Mean distance: 18.33 (cluster 31)
 
Cross-listing: Neurotree

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Publications

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Horwich AL, Fenton WA. (2020) Chaperonin-assisted protein folding: a chronologue. Quarterly Reviews of Biophysics. 53: e4
Taguchi YV, Gorenberg EL, Nagy M, et al. (2019) Hsp110 mitigates α-synuclein pathology in vivo. Proceedings of the National Academy of Sciences of the United States of America
Abdeen S, Kunkle T, Salim N, et al. (2018) Sulfonamido-2-arylbenzoxazole GroEL/ES inhibitors are potent antibacterials against methicillin-resistant Staphylococcus aureus (MRSA). Journal of Medicinal Chemistry
Natesh R, Clare DK, Farr GW, et al. (2018) A two-domain folding intermediate of RuBisCO in complex with the GroEL chaperonin. International Journal of Biological Macromolecules
Thomas EV, Fenton WA, McGrath J, et al. (2017) Transfer of pathogenic and nonpathogenic cytosolic proteins between spinal cord motor neurons in vivo in chimeric mice. Proceedings of the National Academy of Sciences of the United States of America
Zhang Y, Ni W, Horwich AL, et al. (2017) An ALS-associated mutant SOD1 rapidly suppresses KCNT1 (Slack) Na+-activated K+ channels in Aplysia neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience
Hadzipasic M, Ni W, Nagy M, et al. (2016) Reduced high-frequency motor neuron firing, EMG fractionation, and gait variability in awake walking ALS mice. Proceedings of the National Academy of Sciences of the United States of America
Abdeen S, Salim N, Mammadova N, et al. (2016) Targeting the HSP60/10 chaperonin systems of Trypanosoma brucei as a strategy for treating African sleeping sickness. Bioorganic & Medicinal Chemistry Letters
Abdeen S, Salim N, Mammadova N, et al. (2016) GroEL/ES inhibitors as potential antibiotics. Bioorganic & Medicinal Chemistry Letters. 26: 3127-34
Nagy M, Fenton WA, Li D, et al. (2016) Extended survival of misfolded G85R SOD1-linked ALS mice by transgenic expression of chaperone Hsp110. Proceedings of the National Academy of Sciences of the United States of America
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