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Billy W. Day

Pharmaceutical Sciences University of Pittsburgh, Pittsburgh, PA, United States 
Drug Discovery
"Billy Day"
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Robert A. Magarian grad student 1982-1988 University of Oklahoma
 (Synthesis and Biological Evaluation of 1,1-Dichloro-2,2,3-triarylcyclopropanes as Potential Antiestrogens)
Steven R. Tannenbaum post-doc 1988-1991 MIT
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Kaltenmeier CT, Vollmer LL, Vernetti LA, et al. (2017) A tumor cell-selective inhibitor of mitogen-activated protein kinase phosphatases sensitizes breast cancer cells to lymphokine-activated killer cell activity. The Journal of Pharmacology and Experimental Therapeutics
Colombo R, Wang Z, Han J, et al. (2016) Total Synthesis and Biological Evaluation of Tubulysin Analogs. The Journal of Organic Chemistry
Emert-Sedlak LA, Loughran HM, Shi H, et al. (2016) Synthesis and evaluation of orally active small molecule HIV-1 Nef antagonists. Bioorganic & Medicinal Chemistry Letters. 26: 1480-4
Phoa AF, Browne S, Gurgis FM, et al. (2015) Pharmacology of novel small-molecule tubulin inhibitors in glioblastoma cells with enhanced EGFR signalling. Biochemical Pharmacology
Salum LB, Mascarello A, Canevarolo RR, et al. (2015) N-(1'-naphthyl)-3,4,5-trimethoxybenzohydrazide as microtubule destabilizer: Synthesis, cytotoxicity, inhibition of cell migration and in vivo activity against acute lymphoblastic leukemia. European Journal of Medicinal Chemistry. 96: 504-18
Smith SE, Dello Buono MC, Carper DJ, et al. (2014) Structure elucidation of phase I metabolites of the microtubule perturbagens: ceratamines A and B. Journal of Natural Products. 77: 1572-8
Korotchenko VN, Saydmohammed M, Vollmer LL, et al. (2014) In vivo structure-activity relationship studies support allosteric targeting of a dual specificity phosphatase. Chembiochem : a European Journal of Chemical Biology. 15: 1436-45
Gallo MB, Falso MJ, Balem F, et al. (2014) The anti-promyelocytic leukemia mode of action of two endophytic secondary metabolites unveiled by a proteomic approach. Planta Medica. 80: 473-81
Iyer PC, Zhao J, Emert-Sedlak LA, et al. (2014) Synthesis and structure-activity analysis of diphenylpyrazolodiazene inhibitors of the HIV-1 Nef virulence factor. Bioorganic & Medicinal Chemistry Letters. 24: 1702-6
Vollmer L, Vernetti L, Bakan A, et al. (2014) Abstract 745: A non-redox reactive allosteric inhibitor of MAPK phosphatases with selective toxicity to human cancer cells Cancer Research. 74: 745-745
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