Fritz Eckstein
Affiliations: | Max-Planck-Institute for Experimental Medicine, Göttingen, Germany |
Website:
http://oolife.adw-goe.de/members/6-fritz-ecksteinGoogle:
"Fritz Eckstein"Mean distance: 6.84 | S | N | B | C | P |
Parents
Sign in to add mentorBurckhardt Helferich | grad student | 1960 | University of Bonn |
Robert B. Woodward | post-doc | 1964 | Harvard |
Children
Sign in to add traineeThomas Tuschl | grad student | 1995 | University of Regensburg |
Barry V. L. Potter | post-doc | 1981-1983 | Max-Planck-Institute for Experimental Medicine in Goettingen |
Snorri Thor Sigurdsson | post-doc | 1996 | MPI for Experimental Medicine |
Bhisma K. Patel | post-doc | 1994-1997 | MPI for Experimental Medicine |
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Publications
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Eckstein F. (2014) Phosphorothioates, essential components of therapeutic oligonucleotides. Nucleic Acid Therapeutics. 24: 374-87 |
Bramlage B, Luzi E, Eckstein F. (2000) HIV-1 LTR as a target for synthetic ribozyme-mediated inhibition of gene expression: Site selection and inhibition in cell culture Nucleic Acids Research. 28: 4059-4067 |
Kore AR, Vaish NK, Morris JA, et al. (2000) In vitro evolution of the hammerhead ribozyme to a purine-specific ribozyme using mutagenic PCR with two nucleotide analogues. Journal of Molecular Biology. 301: 1113-21 |
Eckstein F, Bramlage B. (1999) The hammerhead ribozyme Biopolymers. 52: 147-154 |
Kore AR, Eckstein F. (1999) Hammerhead ribozyme mechanism: A ribonucleotide 5' to the substrate cleavage site is not essential Biochemistry. 38: 10915-10918 |
Carola C, Eckstein F. (1999) Nucleic acid enzymes Current Opinion in Chemical Biology. 3: 274-283 |
Citti L, Eckstein F, Capecchi B, et al. (1999) Transient transfection of a synthetic hammerhead ribozyme targeted against human MGMT gene to cells in culture potentiates the genotoxicity of the alkylation damage induced by mitozolomide Antisense and Nucleic Acid Drug Development. 9: 125-133 |
Vörtler CS, Fedorova O, Persson T, et al. (1998) Determination of 2'-hydroxyl and phosphate groups important for aminoacylation of Escherichia coli tRNA(Asp): A nucleotide analogue interference study Rna. 4: 1444-1454 |
Alefelder S, Patel BK, Eckstein F. (1998) Incorporation of terminal phosphorothioates into oligonucleotides Nucleic Acids Research. 26: 4983-4988 |
Venna S, Eckstein F. (1998) Modified oligonucleotides: Synthesis and strategy for users Annual Review of Biochemistry. 67: 99-134 |