Brian R. Kupchak, Ph.D.

Affiliations: 
2008 University of Florida, Gainesville, Gainesville, FL, United States 
Area:
Biochemistry, Molecular Biology, Inorganic Chemistry
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"Brian Kupchak"
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Thomas J. Lyons grad student 2008 UF Gainesville
 (The PAQR family of membrane proteins in Saccharomyces cerevisiae: Their role in signal transduction and flow cytometric analysis of AdipoR1 binding to adiponectin and TNF-alpha.)
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Publications

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Garitaonandia I, Smith JL, Kupchak BR, et al. (2009) Adiponectin identified as an agonist for PAQR3/RKTG using a yeast-based assay system. Journal of Receptor and Signal Transduction Research. 29: 67-73
Kupchak BR, Garitaonandia I, Villa NY, et al. (2009) Antagonism of human adiponectin receptors and their membrane progesterone receptor paralogs by TNFalpha and a ceramidase inhibitor. Biochemistry. 48: 5504-6
Villa NY, Kupchak BR, Garitaonandia I, et al. (2009) Sphingolipids function as downstream effectors of a fungal PAQR. Molecular Pharmacology. 75: 866-75
Kupchak BR, Villa NY, Kulemina LV, et al. (2008) Dissecting the regulation of yeast genes by the osmotin receptor. Biochemical and Biophysical Research Communications. 374: 210-3
Smith JL, Kupchak BR, Garitaonandia I, et al. (2008) Heterologous expression of human mPRalpha, mPRbeta and mPRgamma in yeast confirms their ability to function as membrane progesterone receptors. Steroids. 73: 1160-73
Kupchak BR, Garitaonandia I, Villa NY, et al. (2007) Probing the mechanism of FET3 repression by Izh2p overexpression. Biochimica Et Biophysica Acta. 1773: 1124-32
Lyons TJ, Villa NY, Regalla LM, et al. (2004) Metalloregulation of yeast membrane steroid receptor homologs. Proceedings of the National Academy of Sciences of the United States of America. 101: 5506-11
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