Nirupama Gupta, Ph.D.

Affiliations: 
2011 University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Biochemistry
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"Nirupama Gupta"
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Stephen W. Ragsdale grad student 2011 University of Michigan
 (Thiol-based redox modulation of transcriptional regulators; CprK and Rev-erbbeta.)
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Publications

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Carter EL, Gupta N, Ragsdale SW. (2015) High Affinity Heme Binding to a Heme Regulatory Motif on the Nuclear Receptor Rev-erbβ Leads to its Degradation and Indirectly Regulates its Interaction with Nuclear Receptor Corepressor. The Journal of Biological Chemistry
French RL, Gupta N, Copeland PR, et al. (2014) Structural asymmetry of the terminal catalytic complex in selenocysteine synthesis. The Journal of Biological Chemistry. 289: 28783-94
Gonzalez-Flores JN, Gupta N, DeMong LW, et al. (2012) The selenocysteine-specific elongation factor contains a novel and multi-functional domain. The Journal of Biological Chemistry. 287: 38936-45
Ragsdale SW, Yi L, Bender G, et al. (2012) Redox, haem and CO in enzymatic catalysis and regulation. Biochemical Society Transactions. 40: 501-7
Gupta N, Ragsdale SW. (2011) Thiol-disulfide redox dependence of heme binding and heme ligand switching in nuclear hormone receptor rev-erb{beta}. The Journal of Biological Chemistry. 286: 4392-403
Gupta N, Ragsdale SW. (2008) Dual roles of an essential cysteine residue in activity of a redox-regulated bacterial transcriptional activator. The Journal of Biological Chemistry. 283: 28721-8
Pop SM, Gupta N, Raza AS, et al. (2006) Transcriptional activation of dehalorespiration. Identification of redox-active cysteines regulating dimerization and DNA binding. The Journal of Biological Chemistry. 281: 26382-90
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