Jakob Fuhrmann

2016 Chemistry The Scripps Research Institute, Scripps Florida 
"Jakob Fuhrmann"
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Bashore C, Jaishankar P, Skelton NJ, et al. (2020) Cyanopyrrolidine Inhibitors of Ubiquitin Specific Protease 7 Mediate Desulfhydration of the Active-Site Cysteine. Acs Chemical Biology
Brust R, Lin H, Fuhrmann J, et al. (2017) Modification of the Orthosteric PPARγ Covalent Antagonist Scaffold Yields an Improved Dual-Site Allosteric Inhibitor. Acs Chemical Biology
Hughes TS, Shang J, Brust R, et al. (2016) Probing the Complex Binding Modes of the PPARγ Partial Agonist 2-chloro-N-(3-chloro-4-((5-chlorobenzo[d]thiazol-2-yl)thio)phenyl)-4-(trifluoromethyl)benzenesulfonamide (T2384) to Orthosteric and Allosteric Sites with NMR Spectroscopy. Journal of Medicinal Chemistry
Fuhrmann J, Subramanian V, Kojetin DJ, et al. (2016) Activity-Based Profiling Reveals a Regulatory Link between Oxidative Stress and Protein Arginine Phosphorylation. Cell Chemical Biology
Fuhrmann J, Thompson PR. (2015) Protein Arginine Methylation and Citrullination in Epigenetic Regulation. Acs Chemical Biology
Fuhrmann J, Subramanian V, Thompson PR. (2015) Synthesis and Use of a Phosphonate Amidine to Generate an Anti-Phosphoarginine-Specific Antibody. Angewandte Chemie (International Ed. in English)
Fuhrmann J, Clancy KW, Thompson PR. (2015) Chemical Biology of Protein Arginine Modifications in Epigenetic Regulation. Chemical Reviews. 115: 5413-61
Slade DJ, Fang P, Dreyton CJ, et al. (2015) Protein arginine deiminase 2 binds calcium in an ordered fashion: implications for inhibitor design. Acs Chemical Biology. 10: 1043-53
Schmidt A, Trentini DB, Spiess S, et al. (2014) Quantitative Phosphoproteomics Reveals the Role of Protein Arginine Phosphorylation in the Bacterial Stress Response. Molecular & Cellular Proteomics : McP. 13: 537-550
Wang M, Fuhrmann J, Thompson PR. (2014) Protein arginine methyltransferase 5 catalyzes substrate dimethylation in a distributive fashion. Biochemistry. 53: 7884-92
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