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Carston R. Wagner

Medicinal Chemistry University of Minnesota, Twin Cities, Minneapolis, MN 
development of approaches that will deliver anticancers drug, proteins and nucleic acids to cancer tissues and not normal tissues
"Carston R. Wagner"

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Ned A. Porter grad student 1987 Duke
 (Isolation and Characterization of the Primary Products of Phospholipid and Diacylglycerol Peroxidation)
Stephen J. Benkovic post-doc 1987-1991 Penn State


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Jonathan C. Carlson grad student 2005 UMN
Haiqing Wang grad student 2005 UMN
Tsui-Fen Chou grad student 2006 UMN
Yan Jia grad student 2010 UMN
Xin Zhou grad student 2010 UMN
Kari A. Gabrielse grad student 2013 UMN
Amit Gangar grad student 2014 UMN
Sidath C. Kumarapperuma post-doc
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Strom A, Shah R, Wagner CR. (2021) "Switching On" Enzyme Substrate Specificity Analysis with a Fluorescent Competitive Inhibitor. Biochemistry
Wang Y, Kilic O, Csizmar CM, et al. (2020) Engineering reversible cell-cell interactions using enzymatically lipidated chemically self-assembled nanorings. Chemical Science. 12: 331-340
Jacobson BA, Ahmad Z, Chen S, et al. (2020) 4Ei-10 interdiction of oncogenic cap-mediated translation as therapy for non-small cell lung cancer. Investigational New Drugs
Kilic O, Matos de Souza MR, Almotlak A, et al. (2020) Anti-EGFR Fibronectin Bispecific Chemically Self-Assembling Nanorings (CSANs) Induce Potent T-cell Mediated Anti-Tumor Response and Downregulation of EGFR Signaling and PD-1/PD-L1 Expression. Journal of Medicinal Chemistry
Matos de Souza MR, Cunha MS, Okon A, et al. (2020) and Characterization of the Anti-Zika Virus Activity of ProTides of 2'-C-β-methylguanosine. Acs Infectious Diseases
Strom A, Tong CL, Wagner CR. (2020) Histidine triad nucleotide-binding proteins HINT1 and HINT2 Share Similar Substrate Specificities and Little Affinity for the Signaling Dinucleotide Ap4A. Febs Letters
Ahmad Z, Jacobson BA, McDonald MW, et al. (2020) Repression of oncogenic cap-mediated translation by 4Ei-10 diminishes proliferation, enhances chemosensitivity and alters expression of malignancy-related proteins in mesothelioma. Cancer Chemotherapy and Pharmacology
Shah R, Peterson C, Strom A, et al. (2019) Inhibition of Hint1 Modulates Spinal Nociception and NMDA Evoked Behavior in Mice. Acs Chemical Neuroscience
Csizmar CM, Petersburg J, Perry TJ, et al. (2018) Multivalent Ligand Binding to Cell Membrane Antigens: Defining the Interplay of Affinity, Valency, and Expression Density. Journal of the American Chemical Society
Petersburg J, Shen J, Csizmar CM, et al. (2018) Eradication of Established Tumors by Chemically Self-Assembled Nanoring (CSAN) Targeted T-cells. Acs Nano
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