Shiyu Chen

Affiliations: 
Stanford University, Palo Alto, CA 
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"Shiyu Chen"
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Zhang H, Chen S. (2021) Cyclic peptide drugs approved in the last two decades (2001-2021). Rsc Chemical Biology. 3: 18-31
Chen S, Lovell S, Lee S, et al. (2020) Identification of highly selective covalent inhibitors by phage display. Nature Biotechnology
Chen S, Yim JJ, Bogyo M. (2019) Synthetic and biological approaches to map substrate specificities of proteases. Biological Chemistry
Baeriswyl V, Calzavarini S, Chen S, et al. (2015) A Synthetic Factor XIIa Inhibitor Blocks Selectively Intrinsic Coagulation Initiation. Acs Chemical Biology. 10: 1861-70
Chen S, Heinis C. (2015) Phage selection of bicyclic peptides based on two disulfide bridges. Methods in Molecular Biology (Clifton, N.J.). 1248: 119-37
Chen S, Gopalakrishnan R, Schaer T, et al. (2014) Dithiol amino acids can structurally shape and enhance the ligand-binding properties of polypeptides. Nature Chemistry. 6: 1009-16
Bellotto S, Chen S, Rentero Rebollo I, et al. (2014) Phage selection of photoswitchable peptide ligands. Journal of the American Chemical Society. 136: 5880-3
Chen S, Bertoldo D, Angelini A, et al. (2014) Peptide ligands stabilized by small molecules. Angewandte Chemie (International Ed. in English). 53: 1602-6
Chen S, Touati J, Heinis C. (2014) Tracking chemical reactions on the surface of filamentous phage using mass spectrometry. Chemical Communications (Cambridge, England). 50: 5267-9
Chen S, Gfeller D, Buth SA, et al. (2013) Improving binding affinity and stability of peptide ligands by substituting glycines with D-amino acids. Chembiochem : a European Journal of Chemical Biology. 14: 1316-22
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