Kiran V. Mahasenan, Ph.D.
Affiliations: | 2012 | Pharmacy | Ohio State University, Columbus, Columbus, OH |
Area:
PharmacyGoogle:
"Kiran Mahasenan"Bio:
http://rave.ohiolink.edu/etdc/view?acc_num=osu1332367560
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Parents
Sign in to add mentor| Chenglong Li | grad student | 2012 | Ohio State (Chemistry Tree) | |
| (Discovery of novel small molecule enzyme inhibitors and receptor modulators through structure-based computational design.) | ||||
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Publications
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| Qian Y, Allegretta G, Janardhanan J, et al. (2020) Exploration of the Structural Space in 4()-Quinazolinone Antibacterials. Journal of Medicinal Chemistry |
| Alcorlo M, Dik DA, De Benedetti S, et al. (2019) Structural basis of denuded glycan recognition by SPOR domains in bacterial cell division. Nature Communications. 10: 5567 |
| Janardhanan J, Bouley R, Martínez-Caballero S, et al. (2019) The quinazolinone allosteric inhibitor of PBP2a synergizes with piperacillin and tazobactam against methicillin-resistant . Antimicrobial Agents and Chemotherapy |
| Dik DA, Batuecas MT, Lee M, et al. (2018) A Structural Dissection of the Active Site of the Lytic Transglycosylase MltE from Escherichia coli. Biochemistry |
| Mahasenan KV, Ding D, Gao M, et al. (2018) In Search of Selectivity in Inhibition of ADAM10. Acs Medicinal Chemistry Letters. 9: 708-713 |
| Byun B, Mahasenan KV, Dik DA, et al. (2018) Mechanism of the Escherichia coli MltE lytic transglycosylase, the cell-wall-penetrating enzyme for Type VI secretion system assembly. Scientific Reports. 8: 4110 |
| Bernardo-Garcia N, Mahasenan KV, Batuecas MT, et al. (2018) Allostery, Recognition of Nascent Peptidoglycan and Crosslinking of the Cell Wall by the Essential Penicillin-Binding Protein 2x of Streptococcus pneumoniae. Acs Chemical Biology |
| Lee M, Batuecas MT, Tomoshige S, et al. (2018) Exolytic and endolytic turnover of peptidoglycan by lytic transglycosylase Slt ofPseudomonas aeruginosa. Proceedings of the National Academy of Sciences of the United States of America. 115: 4393-4398 |
| Mahasenan KV, Bastian M, Gao M, et al. (2017) Exploitation of Conformational Dynamics in Imparting Selective Inhibition for Related Matrix Metalloproteinases. Acs Medicinal Chemistry Letters. 8: 654-659 |
| Acebron I, Mahasenan KV, De Benedetti S, et al. (2017) Catalytic Cycle of the N-Acetylglucosaminidase NagZ from Pseudomonas aeruginosa. Journal of the American Chemical Society |