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Peter F. Leadlay

Affiliations: 
Biochemistry University of Cambridge, Cambridge, England, United Kingdom 
Area:
Biosynthesis of Polyketide Antibiotics
Website:
http://www.bio.cam.ac.uk/~pflgroup/
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"Peter F. Leadlay"
Bio:

http://www.bioc.cam.ac.uk/uto/leadlay

Mean distance: 7.4
 
SNBCP

Parents

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Jeremy R. Knowles grad student 1974 Oxford
Duilio Arigoni post-doc 1974-1976 ETH Zürich

Children

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Nicolas H. Thomä grad student
E. Neil G. Marsh grad student 1988 Cambridge
Jeroen S. Dickschat grad student 2006-2008 Cambridge
David H. Kwan grad student 2005-2009 Cambridge
Frank Schulz post-doc
Frank Hahn post-doc 2009-2011 Cambridge
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Publications

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Xu J, Zhang X, Huang F, et al. (2021) Efophylins A and B, Two -Asymmetric Macrodiolide Immunosuppressants from . Journal of Natural Products
de Paiva FCR, Chan K, Samborskyy M, et al. (2020) The crystal structure of AjiA1 reveals a novel structural motion mechanism in the adenylate-forming enzyme family. Acta Crystallographica. Section D, Structural Biology. 76: 1201-1210
Little RF, Samborskyy M, Leadlay PF. (2020) The biosynthetic pathway to tetromadurin (SF2487/A80577), a polyether tetronate antibiotic. Plos One. 15: e0239054
Zhai G, Wang W, Xu W, et al. (2020) Cross-module Enoylreduction in the Azalomycin F Polyketide Synthase. Angewandte Chemie (International Ed. in English)
Shen Y, Sun F, Zhang L, et al. (2020) Biosynthesis of depsipeptides with a 3-hydroxybenzoate moiety and selective anticancer activities involves a chorismatase. The Journal of Biological Chemistry
Koomsiri W, Inahashi Y, Leetanasaksakul K, et al. (2019) Sarpeptins A and B, Lipopeptides Produced by sp. KO-7888 Overexpressing a Specific SARP Regulator. Journal of Natural Products
Bilyk O, Samborskyy M, Leadlay PF. (2019) The biosynthetic pathway to ossamycin, a macrocyclic polyketide bearing a spiroacetal moiety. Plos One. 14: e0215958
de Araújo NC, Bury PDS, Tavares MT, et al. (2019) Crystal Structure of GenD2, an NAD-Dependent Oxidoreductase Involved in the Biosynthesis of Gentamicin. Acs Chemical Biology
Hong H, Samborskyy M, Zhou Y, et al. (2019) C-Nucleoside Formation in the Biosynthesis of the Antifungal Malayamycin A. Cell Chemical Biology
Häckh M, Lucas X, Marolt M, et al. (2019) Hidden Specificities in Enzyme Catalysis: Structural Basis of Substrate Structure-Selectivity Relationship of a Ketoreductase. Chembiochem : a European Journal of Chemical Biology
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