Peter F. Leadlay
Affiliations: | Biochemistry | University of Cambridge, Cambridge, England, United Kingdom |
Area:
Biosynthesis of Polyketide AntibioticsWebsite:
http://www.bio.cam.ac.uk/~pflgroup/Google:
"Peter F. Leadlay"Bio:
http://www.bioc.cam.ac.uk/uto/leadlay
Mean distance: 7.4 | S | N | B | C | P |
Parents
Sign in to add mentorJeremy R. Knowles | grad student | 1974 | Oxford |
Duilio Arigoni | post-doc | 1974-1976 | ETH Zürich |
Children
Sign in to add traineeNicolas H. Thomä | grad student | ||
E. Neil G. Marsh | grad student | 1988 | Cambridge |
Jeroen S. Dickschat | grad student | 2006-2008 | Cambridge |
David H. Kwan | grad student | 2005-2009 | Cambridge |
Frank Schulz | post-doc | ||
Barrie Wilkinson | post-doc | 1995-1997 | University of Cambridge (UK) |
Frank Hahn | post-doc | 2009-2011 | Cambridge |
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Publications
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Bilyk O, Oliveira GS, de Angelo RM, et al. (2022) Enzyme-Catalyzed Spiroacetal Formation in Polyketide Antibiotic Biosynthesis. Journal of the American Chemical Society. 144: 14555-14563 |
Little RF, Samborskyy M, Leadlay PF. (2020) The biosynthetic pathway to tetromadurin (SF2487/A80577), a polyether tetronate antibiotic. Plos One. 15: e0239054 |
Zhai G, Wang W, Xu W, et al. (2020) Cross-module Enoylreduction in the Azalomycin F Polyketide Synthase. Angewandte Chemie (International Ed. in English) |
Shen Y, Sun F, Zhang L, et al. (2020) Biosynthesis of depsipeptides with a 3-hydroxybenzoate moiety and selective anticancer activities involves a chorismatase. The Journal of Biological Chemistry |
Koomsiri W, Inahashi Y, Leetanasaksakul K, et al. (2019) Sarpeptins A and B, Lipopeptides Produced by sp. KO-7888 Overexpressing a Specific SARP Regulator. Journal of Natural Products |
Bilyk O, Samborskyy M, Leadlay PF. (2019) The biosynthetic pathway to ossamycin, a macrocyclic polyketide bearing a spiroacetal moiety. Plos One. 14: e0215958 |
de Araújo NC, Bury PDS, Tavares MT, et al. (2019) Crystal Structure of GenD2, an NAD-Dependent Oxidoreductase Involved in the Biosynthesis of Gentamicin. Acs Chemical Biology |
Hong H, Samborskyy M, Zhou Y, et al. (2019) C-Nucleoside Formation in the Biosynthesis of the Antifungal Malayamycin A. Cell Chemical Biology |
Häckh M, Lucas X, Marolt M, et al. (2019) Hidden Specificities in Enzyme Catalysis: Structural Basis of Substrate Structure-Selectivity Relationship of a Ketoreductase. Chembiochem : a European Journal of Chemical Biology |
Häckh M, Lucas X, Marolt M, et al. (2019) Cover Feature: Hidden Specificities in Enzyme Catalysis: Structural Basis of Substrate Structure‐Selectivity Relationship of a Ketoreductase (ChemBioChem 9/2019) Chembiochem. 20: 1090-1090 |