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Uttam L. RajBhandary

Affiliations: 
Molecular Biology Massachusetts Institute of Technology, Cambridge, MA, United States 
Area:
Transfer RNAs, Protein Synthesis, Suppressor tRNAs, RNA-protein Interactions and Proteins Carrying Unnatural Amino Acids
Website:
https://biology.mit.edu/people/uttam_rajbhandary#overview
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"Uttam L. RajBhandary"
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Thiaville PC, El Yacoubi B, Köhrer C, et al. (2015) Essentiality of threonylcarbamoyladenosine (t(6) A), a universal tRNA modification, in bacteria. Molecular Microbiology
Niehues S, Bussmann J, Steffes G, et al. (2015) Impaired protein translation in Drosophila models for Charcot-Marie-Tooth neuropathy caused by mutant tRNA synthetases. Nature Communications. 6: 7520
Bhattacharya A, Köhrer C, Mandal D, et al. (2015) Nonsense suppression in archaea. Proceedings of the National Academy of Sciences of the United States of America. 112: 6015-20
Sinha A, Köhrer C, Weber MH, et al. (2014) Biochemical characterization of pathogenic mutations in human mitochondrial methionyl-tRNA formyltransferase. The Journal of Biological Chemistry. 289: 32729-41
Vercruysse M, Köhrer C, Davies BW, et al. (2014) The highly conserved bacterial RNase YbeY is essential in vibrio cholerae, playing a critical role in virulence, stress regulation, and RNA processing. Plos Pathogens. 10: e1004175
Mandal D, Köhrer C, Su D, et al. (2014) Identification and codon reading properties of 5-cyanomethyl uridine, a new modified nucleoside found in the anticodon wobble position of mutant haloarchaeal isoleucine tRNAs. Rna (New York, N.Y.). 20: 177-88
Köhrer C, Mandal D, Gaston KW, et al. (2014) Life without tRNAIle-lysidine synthetase: translation of the isoleucine codon AUA in Bacillus subtilis lacking the canonical tRNA2Ile. Nucleic Acids Research. 42: 1904-15
Voorhees RM, Mandal D, Neubauer C, et al. (2013) The structural basis for specific decoding of AUA by isoleucine tRNA on the ribosome. Nature Structural & Molecular Biology. 20: 641-3
Jacob AI, Köhrer C, Davies BW, et al. (2013) Conserved bacterial RNase YbeY plays key roles in 70S ribosome quality control and 16S rRNA maturation. Molecular Cell. 49: 427-38
RajBhandary UL. (2012) Har Gobind Khorana: Early years in science and transition from chemistry to chemical biology Resonance. 17: 1125-1135
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