Michael M. Gottesman

Affiliations: 
Cell Biology National Cancer Institute, Rockville, MD, United States 
Area:
resistance of cancer cells to anticancer drugs
Website:
https://ccr.cancer.gov/Laboratory-of-Cell-Biology/michael-m-gottesman
Google:
"Michael M. Gottesman"
Mean distance: 9.49
 
SNBCP

Children

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Lynn M. Pouliot grad student 2012 Georgetown
Christine A. Hrycyna post-doc 1993-2000 National Cancer Institute
Kevin G. Chen post-doc 2002-2005 NIH (Neurotree)

Collaborators

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Kevin G. Chen collaborator 2005- (Neurotree)
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Publications

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McDonald AJ, Curt KM, Patel RP, et al. (2018) Targeting mitochondrial hexokinases increases efficacy of histone deacetylase inhibitors in solid tumor models. Experimental Cell Research
Vahedi S, Lusvarghi S, Pluchino K, et al. (2018) Mapping discontinuous epitopes for MRK-16, UIC2 and 4E3 antibodies to extracellular loops 1 and 4 of human P-glycoprotein. Scientific Reports. 8: 12716
Chen KG, Mallon BS, Park K, et al. (2018) Pluripotent Stem Cell Platforms for Drug Discovery. Trends in Molecular Medicine
Robey RW, Pluchino KM, Hall MD, et al. (2018) Revisiting the role of ABC transporters in multidrug-resistant cancer. Nature Reviews. Cancer
Esser L, Zhou F, Pluchino KM, et al. (2016) Structures of the Multidrug Transporter P-glycoprotein Reveal Asymmetric ATP Binding and the Mechanism of Polyspecificity. The Journal of Biological Chemistry
Bahr JC, Robey RW, Luchenko V, et al. (2016) Blocking downstream signaling pathways in the context of HDAC inhibition promotes apoptosis preferentially in cells harboring mutant Ras. Oncotarget
Kannan P, Schain M, Kretzschmar WW, et al. (2016) An automated method measures variability in P-glycoprotein and ABCG2 densities across brain regions and brain matter. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism
Bakhsheshian J, Wei BR, Hall MD, et al. (2016) In Vivo Bioluminescent Imaging of ATP-Binding Cassette Transporter-Mediated Efflux at the Blood-Brain Barrier. Methods in Molecular Biology (Clifton, N.J.). 1461: 227-39
Liow JS, Zoghbi SS, Hu S, et al. (2016) (18)F-FCWAY, a serotonin 1A receptor radioligand, is a substrate for efflux transport at the human blood-brain barrier. Neuroimage
Frank G, Shukla S, Rao P, et al. (2016) Cryo-EM analysis of the conformational landscape of human P-glycoprotein (ABCB1) during its catalytic cycle. Molecular Pharmacology
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