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Richard Howard Himes

Affiliations: 
Molecular Biosciences University of Kansas, Lawrence, KS, United States 
Website:
http://www.molecularbiosciences.ku.edu/richard-h-himes
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"Richard Howard Himes"
Bio:

http://chemistry.library.nd.edu/resources/genealogy/chemistry/documents/HimesRH.pdf

Mean distance: 9.87
 
SNBCP

Parents

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Jesse C. Rabinowitz grad student 1961 UC Berkeley
 (Tetrahydrofolic acid formylase)
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Publications

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Entwistle RA, Rizk RS, Cheng DM, et al. (2012) Differentiating between models of epothilone binding to microtubules using tubulin mutagenesis, cytotoxicity, and molecular modeling. Chemmedchem. 7: 1580-6
Reiff EA, Nair SK, Henri JT, et al. (2010) Total synthesis and evaluation of C26-hydroxyepothilone D derivatives for photoaffinity labeling of beta-tubulin. The Journal of Organic Chemistry. 75: 86-94
Hutt OE, Inagaki J, Reddy BS, et al. (2009) Total synthesis and evaluation of 22-(3-azidobenzoyloxy)methyl epothilone C for photoaffinity labeling of beta-tubulin. Bioorganic & Medicinal Chemistry Letters. 19: 3293-6
Winefield RD, Entwistle RA, Foland TB, et al. (2008) Differences in paclitaxel and docetaxel interactions with tubulin detected by mutagenesis of yeast tubulin. Chemmedchem. 3: 1844-7
Ge H, Wang J, Kayser MM, et al. (2008) Synthesis, tubulin assembly, and antiproliferative activity against MCF7 and NCI/ADR-RES cancer cells of 10-O-acetyl-5'-hydroxybutitaxel. Bioorganic & Medicinal Chemistry Letters. 18: 6165-7
Turunen BJ, Ge H, Oyetunji J, et al. (2008) Paclitaxel succinate analogs: Anionic and amide introduction as a strategy to impart blood-brain barrier permeability. Bioorganic & Medicinal Chemistry Letters. 18: 5971-4
Hutt OE, Reddy BS, Nair SK, et al. (2008) Total synthesis and evaluation of C25-benzyloxyepothilone C for tubulin assembly and cytotoxicity against MCF-7 breast cancer cells. Bioorganic & Medicinal Chemistry Letters. 18: 4904-6
Entwistle RA, Winefield RD, Foland TB, et al. (2008) The paclitaxel site in tubulin probed by site-directed mutagenesis of Saccharomyces cerevisiae beta-tubulin. Febs Letters. 582: 2467-70
Ahn YM, Vogeti L, Liu CJ, et al. (2007) Design, synthesis, and antiproliferative and CDK2-cyclin a inhibitory activity of novel flavopiridol analogues. Bioorganic & Medicinal Chemistry. 15: 702-13
Spletstoser JT, Turunen BJ, Desino K, et al. (2006) Single-site chemical modification at C10 of the baccatin III core of paclitaxel and Taxol C reduces P-glycoprotein interactions in bovine brain microvessel endothelial cells. Bioorganic & Medicinal Chemistry Letters. 16: 495-8
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