Jerry Y. Hsu, Ph.D.

Affiliations: 
2004 Stanford University, Palo Alto, CA 
Area:
Cell Biology, Oncology, Molecular Biology
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"Jerry Hsu"
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Parents

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Peter Kent Jackson grad student 2004 Stanford
 (The role of human Emi-1 in the cell cycle and cancer.)
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Publications

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Lehman NL, Tibshirani R, Hsu JY, et al. (2007) Oncogenic regulators and substrates of the anaphase promoting complex/cyclosome are frequently overexpressed in malignant tumors. The American Journal of Pathology. 170: 1793-805
Lehman NL, Verschuren EW, Hsu JY, et al. (2006) Overexpression of the anaphase promoting complex/cyclosome inhibitor Emi1 leads to tetraploidy and genomic instability of p53-deficient cells. Cell Cycle (Georgetown, Tex.). 5: 1569-73
Margottin-Goguet F, Hsu JY, Loktev A, et al. (2003) Prophase destruction of Emi1 by the SCF(betaTrCP/Slimb) ubiquitin ligase activates the anaphase promoting complex to allow progression beyond prometaphase. Developmental Cell. 4: 813-26
Hansen DV, Hsu JY, Kaiser BK, et al. (2002) Control of the centriole and centrosome cycles by ubiquitination enzymes. Oncogene. 21: 6209-21
Hsu JY, Reimann JD, Sørensen CS, et al. (2002) E2F-dependent accumulation of hEmi1 regulates S phase entry by inhibiting APC(Cdh1). Nature Cell Biology. 4: 358-66
Reimann JD, Freed E, Hsu JY, et al. (2001) Emi1 is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex. Cell. 105: 645-55
Jackson PK, Eldridge AG, Freed E, et al. (2000) The lore of the RINGs: substrate recognition and catalysis by ubiquitin ligases. Trends in Cell Biology. 10: 429-39
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