Jürgen Seibel

Affiliations: 
Julius-Maximilans-Universität Würzburg, Würzburg, Bayern, Germany 
Area:
Organic Chemistry
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"Jürgen Seibel"
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Publications

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Ortiz-Soto ME, Baier M, Brenner D, et al. (2023) Single-mutations at the galactose-binding site of enzymes GalK, GalU and LgtC enable the efficient synthesis of UDP-6-azido-6-deoxy-D-galactose and azido-functionalized Gb3 analogs. Glycobiology
Ortiz-Soto ME, Porras-Domínguez JR, Rodríguez-Alegría ME, et al. (2020) Implications of the mutation S164A on Bacillus subtilis levansucrase product specificity and insights into protein interactions acting upon levan synthesis. International Journal of Biological Macromolecules. 161: 898-908
Ortiz-Soto ME, Reising S, Schlosser A, et al. (2019) Structural and functional role of disulphide bonds and substrate binding residues of the human beta-galactoside alpha-2,3-sialyltransferase 1 (hST3Gal1). Scientific Reports. 9: 17993
Ortiz-Soto ME, Porras-Domínguez JR, Seibel J, et al. (2019) A close look at the structural features and reaction conditions that modulate the synthesis of low and high molecular weight fructans by levansucrases. Carbohydrate Polymers. 219: 130-142
Possiel C, Ortiz-Soto ME, Ertl J, et al. (2019) Exploring the sequence variability of polymerization-involved residues in the production of levan- and inulin-type fructooligosaccharides with a levansucrase. Scientific Reports. 9: 7720
Ertl J, Ortiz-Soto ME, Le TA, et al. (2019) Tuning the product spectrum of a glycoside hydrolase enzyme by a combination of site-directed mutagenesis and tyrosine-specific chemical modification. Chemistry (Weinheim An Der Bergstrasse, Germany)
Ertl J, Ortiz‐Soto ME, Le TA, et al. (2019) Cover Feature: Tuning the Product Spectrum of a Glycoside Hydrolase Enzyme by a Combination of Site‐Directed Mutagenesis and Tyrosine‐Specific Chemical Modification (Chem. Eur. J. 26/2019) Chemistry – a European Journal. 25: 6456-6456
Ortiz-Soto ME, Ertl J, Mut J, et al. (2018) Product-oriented chemical surface modification of a levansucrase (SacB) an ene-type reaction. Chemical Science. 9: 5312-5321
Kaiser D, Winne JM, Ortiz-Soto ME, et al. (2018) Mechanistical insights into the bioconjugation reaction of Triazolinediones with tyrosine. The Journal of Organic Chemistry
Fink J, Seibel J. (2018) Click reactions with functional sphingolipids. Biological Chemistry
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