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William J. Kerr

Pure & Applied Chemistry University of Strathclyde, Glasgow, Scotland, United Kingdom 
metal-mediated synthetic organic chemistry
"William J. Kerr"

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Kerr WJ, Knox GJ, Reid M, et al. (2021) Catalyst design in C-H activation: a case study in the use of binding free energies to rationalise intramolecular directing group selectivity in iridium catalysis. Chemical Science. 12: 6747-6755
Kerr WJ, Knox GJ, Reid M, et al. (2020) Computationally-Guided Development of a Chelated NHC-P Iridium(I) Complex for the Directed Hydrogen Isotope Exchange of Aryl Sulfones. Acs Catalysis. 10: 11120-11126
Wellaway CR, Bamborough P, Bernard SG, et al. (2020) Structure-Based Design of a Bromodomain and Extraterminal Domain (BET) Inhibitor Selective for the N-Terminal Bromodomains That Retains an Anti-inflammatory and Antiproliferative Phenotype. Journal of Medicinal Chemistry
Queen AE, Hesk D, Lindsay DM, et al. (2020) Synthesis of [ H] and [ C]Genipin. Journal of Labelled Compounds & Radiopharmaceuticals
Timofeeva DS, Lindsay DM, Kerr WJ, et al. (2020) A quantitative empirical directing group scale for selectivity in iridium-catalysed hydrogen isotope exchange reactions Catalysis Science & Technology
Simionesie D, O’Callaghan G, Costa JLLFS, et al. (2020) Clustering behaviour of polyaromatic compounds mimicking natural asphaltenes Colloids and Surfaces a: Physicochemical and Engineering Aspects. 603: 125221
Kerr WJ, Knox GJ, Paterson LC. (2019) Recent Advances in Iridium(I) Catalysis towards Directed Hydrogen Isotope Exchange. Journal of Labelled Compounds & Radiopharmaceuticals
Barrett TN, Taylor JA, Barker D, et al. (2019) Profile of a Highly Selective Quaternized Pyrrolidine Betaine αβ Integrin Inhibitor-(3)-3-(3-(3,5-Dimethyl-1-pyrazol-1-yl)phenyl)-4-((1 and 1,3)-1-methyl-3-(2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl)pyrrolidin-1-ium-1-yl)butanoate Synthesized by Stereoselective Methylation. Journal of Medicinal Chemistry
Tinworth CP, Lithgow H, Dittus L, et al. (2019) PROTAC-Mediated Degradation of Bruton's Tyrosine Kinase Is Inhibited by Covalent Binding. Acs Chemical Biology
Javadi Y, MacLeod CN, Pierce S, et al. (2019) Ultrasonic phased array inspection of wire + arc additive manufacture samples using conventional and total focusing method imaging approaches Insight. 61: 144-148
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