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David R. Davies, Ph.D.

Affiliations: 
NIDDK, NIH, Bethesda, MD, United States 
Area:
structural biology, crystallography, innate immune system
Website:
http://www-mslmb.niddk.nih.gov/davies/david.html
Google:
"David Davies"
Bio:

http://www.nasonline.org/member-directory/members/56487.html
http://www-mslmb.niddk.nih.gov/davies/davieslab.html
http://www.biophysics.org/Portals/1/PDFs/Career%20Center/Profiles/davies.pdf

Mean distance: 7.36
 		SNBCP
Cross-listing: Crystallography Tree

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Parents

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Herbert Marcus Powell grad student 1952 Oxford
Linus Carl Pauling post-doc 1952-1954 Caltech
 (Noyes Fellowship)

Children

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Brian W. Matthews post-doc 1967-1969 NIH

Collaborators

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Publications

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Botos I, Segal DM, Davies DR. (2011) The structural biology of Toll-like receptors. Structure (London, England : 1993). 19: 447-59
Wang Y, Liu L, Davies DR, et al. (2010) Dimerization of Toll-like receptor 3 (TLR3) is required for ligand binding. The Journal of Biological Chemistry. 285: 36836-41
Li M, Chen C, Davies DR, et al. (2010) Induced-fit mechanism for prolyl endopeptidase. The Journal of Biological Chemistry. 285: 21487-95
Fitzkee NC, Masse JE, Shen Y, et al. (2010) Solution conformation and dynamics of the HIV-1 integrase core domain. The Journal of Biological Chemistry. 285: 18072-84
Botos I, Liu L, Wang Y, et al. (2009) The toll-like receptor 3:dsRNA signaling complex. Biochimica Et Biophysica Acta. 1789: 667-74
Liu L, Botos I, Wang Y, et al. (2008) Structural basis of toll-like receptor 3 signaling with double-stranded RNA. Science (New York, N.Y.). 320: 379-81
Leonard JN, Ghirlando R, Askins J, et al. (2008) The TLR3 signaling complex forms by cooperative receptor dimerization. Proceedings of the National Academy of Sciences of the United States of America. 105: 258-63
Bell JK, Botos I, Hall PR, et al. (2006) The molecular structure of the TLR3 extracellular domain. Journal of Endotoxin Research. 12: 375-8
Bell JK, Askins J, Hall PR, et al. (2006) The dsRNA binding site of human Toll-like receptor 3. Proceedings of the National Academy of Sciences of the United States of America. 103: 8792-7
Kubelka J, Chiu TK, Davies DR, et al. (2006) Sub-microsecond protein folding. Journal of Molecular Biology. 359: 546-53
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