Brian M. Baker

Affiliations: 
Chemistry and Biochemistry University of Notre Dame, Notre Dame, IN, United States 
Area:
molecular recognition and cellular communication
Website:
http:/bmblab.org
Google:
"Brian M. Baker"
Bio:

http://www.bmblab.org
http://physics.library.nd.edu/resources/genealogy/chemistry/documents/BakerBM.pdf

Mean distance: 8.37
 
SNBCP

Parents

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Kenneth P. Murphy grad student 1997 University of Iowa
 (Studies on the binding of ovomucoid third domain to elastase: towards the accurate prediction of binding energetics from structure)
Don C. Wiley post-doc 2001 Harvard

Children

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Rebecca Davis-Harrison grad student 2007 Notre Dame
Kathryn M. Armstrong grad student 2009 Notre Dame
Francis K. Insaidoo grad student 2010 Notre Dame
Kurt H. Piepenbrink grad student 2011 Notre Dame
Brian E. Gloor grad student 2012 Notre Dame
Daniel R. Scott grad student 2012 Notre Dame
Moushumi Hossain grad student 2013 Notre Dame
Sydney J. Blevins grad student 2016 Notre Dame
Corey A.K. Ayres grad student 2017 Notre Dame
Timothy Riley grad student 2017 Notre Dame
Yuan Wang grad student 2017 Notre Dame
Nishant K Singh grad student 2018 Notre Dame
Jesus Alonso post-doc 2017- Notre Dame
Oleg Y. Borbulevych post-doc 2008 Notre Dame
Sujatha Santhanagopalan post-doc 2009 Notre Dame
William F. Hawse post-doc 2013 Notre Dame
Lance M. Hellman post-doc 2013 Notre Dame
BETA: Related publications

Publications

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Tarbe M, Miles JJ, Edwards ESJ, et al. (2020) Synthesis and biological evaluation of hapten-clicked analogues of the antigenic peptide Melan-A/MART-126(27L)-35. Chemmedchem
Spear TT, Evavold BD, Baker BM, et al. (2019) Understanding TCR affinity, antigen specificity, and cross-reactivity to improve TCR gene-modified T cells for cancer immunotherapy. Cancer Immunology, Immunotherapy : Cii
Singh NK, Abualrous ET, Ayres CM, et al. (2019) Geometrical characterization of T cell receptor binding modes reveals class-specific binding to maximize access to antigen. Proteins
Riley TP, Keller GLJ, Smith AR, et al. (2019) Structure Based Prediction of Neoantigen Immunogenicity. Frontiers in Immunology. 10: 2047
McGrath E, Waschbüsch D, Baker BM, et al. (2019) LRRK2 binds to the Rab32 subfamily in a GTP-dependent manner its armadillo domain. Small Gtpases. 1-14
Ayres CM, Abualrous ET, Bailey A, et al. (2019) Dynamically Driven Allostery in MHC Proteins: Peptide-Dependent Tuning of Class I MHC Global Flexibility. Frontiers in Immunology. 10: 966
Hellman LM, Foley KC, Singh NK, et al. (2018) Improving T Cell Receptor On-Target Specificity via Structure-Guided Design. Molecular Therapy : the Journal of the American Society of Gene Therapy
Riley TP, Baker BM. (2018) The intersection of affinity and specificity in the development and optimization of T cell receptor based therapeutics. Seminars in Cell & Developmental Biology. 84: 30-41
Riley TP, Hellman LM, Gee MH, et al. (2018) T cell receptor cross-reactivity expanded by dramatic peptide-MHC adaptability. Nature Chemical Biology. 14: 934-942
Eby JM, Smith AR, Riley TP, et al. (2018) Molecular properties of gp100-reactive T cell receptors drive the cytokine profile and antitumor efficacy of transgenic host T cells. Pigment Cell & Melanoma Research
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