Paul M. Helquist

Affiliations: 
1974-1986 Stony Brook University, Stony Brook, NY, United States 
 1984- Chemistry and Biochemistry University of Notre Dame, Notre Dame, IN, United States 
Area:
Drug Design & Discovery, Synthetic Chemistry
Website:
http://chemistry.nd.edu/people/paul-helquist/
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"Paul M. Helquist"
Bio:

http://harpercancer.nd.edu/people/paul-helquist/
http://chemistry.library.nd.edu/resources/genealogy/chemistry/documents/HelquistPM.pdf

Mean distance: 7.2
 
SNBCP

Parents

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Martin F. Semmelhack grad student 1972 Cornell
 (Applications of zerovalent nickel complexes to synthetic organic chemistry)
Elias James Corey post-doc 1973-1974 Harvard

Children

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Daniel Strand research assistant 2001 Notre Dame
William M. Wuest research assistant 2001-2003 Notre Dame
Farbod Salahi grad student Notre Dame
Anthony Marfat grad student 1974-1978 SUNY Stony Brook
Joel Berniac grad student 2000 Notre Dame
Joshua S. Tullis grad student 2000 Notre Dame
John J. Kane grad student 2003 Notre Dame
Jacob M. Plummer grad student 2008 Notre Dame
Douglas J. Schauer grad student 2008 Notre Dame
Jeffrey M. Carney grad student 2003-2009 Notre Dame
Casey C. Cosner grad student 2011 Notre Dame
John T. Markiewicz grad student 2011 Notre Dame
Pauline Bourbon grad student 2013 Notre Dame
Joshua M. Lee grad student 2014 Notre Dame
Katherine Byrd grad student 2010-2015 Notre Dame
Anthony Rosales grad student 2014-2019
B Mikael Bergdahl post-doc Notre Dame
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Publications

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Rosales A, Ross SP, Helquist P, et al. (2020) Transition State Force Field for the Asymmetric Redox Relay Heck Reaction. Journal of the American Chemical Society
Purohit V, Rosales T, Critchelow C, et al. (2020) Developing a pH-Jump Chemical Triggering Method for Time-Resolved Diffraction in Bacterial HMG-CoA Reductase Biophysical Journal. 118: 137a
Davidson J, Molitor E, Moores S, et al. (2019) 2-Hydroxypropyl-β-cyclodextrin is the active component in a triple combination formulation for treatment of Niemann-Pick C1 disease. Biochimica Et Biophysica Acta. Molecular and Cell Biology of Lipids
Purohit V, Steussy C, Schmidt T, et al. (2019) Time-Resolved Crystallography Measurements Elucidating the Mechanism of Bacterial HMG-CoA Reductase Biophysical Journal. 116: 16a
Rosales AR, Quinn TR, Wahlers J, et al. (2018) Application of Q2MM to predictions in stereoselective synthesis. Chemical Communications (Cambridge, England)
Salahi F, Purohit V, Ferraudi G, et al. (2018) pHP-Tethered N-Acyl Carbamate: A Photocage for Nicotinamide. Organic Letters. 20: 2547-2550
Rosales AR, Wahlers J, Limé E, et al. (2018) Rapid virtual screening of enantioselective catalysts using CatVS Nature Catalysis. 2: 41-45
Zhang X, Tutkowski B, Oliver A, et al. (2018) Mechanistic Study of the Nickel-Catalyzed α,β-Coupling of Saturated Ketones Acs Catalysis. 8: 1740-1747
Tutkowski B, Kerdphon S, Limé E, et al. (2017) Revisiting the Stereodetermining Step in Enantioselective Iridium-Catalyzed Imine Hydrogenation Acs Catalysis. 8: 615-623
Grigalunas M, Wiest O, Helquist P. (2016) Single-Flask Multicomponent Synthesis of Highly Substituted α-Pyrones via a Sequential Enolate Arylation and Alkenylation Strategy. Organic Letters. 18: 5724-5727
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