Vasant Jadhav

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1998 CSIR-National Chemical Laboratory, Pune, India 
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"Vasant Jadhav"
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Jadhav V, Vaishnaw A, Fitzgerald K, et al. (2024) RNA interference in the era of nucleic acid therapeutics. Nature Biotechnology. 42: 394-405
Subramanian M, McIninch J, Zlatev I, et al. (2023) RNAi-mediated rheostat for dynamic control of AAV-delivered transgenes. Nature Communications. 14: 1970
Schlegel MK, Janas MM, Jiang Y, et al. (2022) From bench to bedside: Improving the clinical safety of GalNAc-siRNA conjugates using seed-pairing destabilization. Nucleic Acids Research
Brown KM, Nair JK, Janas MM, et al. (2022) Expanding RNAi therapeutics to extrahepatic tissues with lipophilic conjugates. Nature Biotechnology
Jahns H, Degaonkar R, Podbevsek P, et al. (2021) Small circular interfering RNAs (sciRNAs) as a potent therapeutic platform for gene-silencing. Nucleic Acids Research
Klein D, Goldberg S, Theile CS, et al. (2021) Centyrin Ligands for Extrahepatic Delivery of siRNA. Molecular Therapy : the Journal of the American Society of Gene Therapy
Brown CR, Gupta S, Qin J, et al. (2020) Investigating the pharmacodynamic durability of GalNAc-siRNA conjugates. Nucleic Acids Research
Kumar P, Parmar RG, Brown CR, et al. (2019) 5'-Morpholino modification of the sense strand of an siRNA makes it a more effective passenger. Chemical Communications (Cambridge, England)
Janas MM, Zlatev I, Liu J, et al. (2019) Safety evaluation of 2'-deoxy-2'-fluoro nucleotides in GalNAc-siRNA conjugates. Nucleic Acids Research
Zewge D, Butora G, Sherer EC, et al. (2018) Post-Synthetic Modification of Oligonucleotides via Orthogonal Amidation and Copper Catalyzed Cycloaddition Reactions. Bioconjugate Chemistry
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