Vasant Jadhav
Affiliations: | 1998 | CSIR-National Chemical Laboratory, Pune, India |
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Sign in to add mentorKrishna N. Ganesh | grad student | 1998 | CSIR-National Chemical Laboratory, Pune, India |
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Publications
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Jadhav V, Vaishnaw A, Fitzgerald K, et al. (2024) RNA interference in the era of nucleic acid therapeutics. Nature Biotechnology. 42: 394-405 |
Subramanian M, McIninch J, Zlatev I, et al. (2023) RNAi-mediated rheostat for dynamic control of AAV-delivered transgenes. Nature Communications. 14: 1970 |
Schlegel MK, Janas MM, Jiang Y, et al. (2022) From bench to bedside: Improving the clinical safety of GalNAc-siRNA conjugates using seed-pairing destabilization. Nucleic Acids Research |
Brown KM, Nair JK, Janas MM, et al. (2022) Expanding RNAi therapeutics to extrahepatic tissues with lipophilic conjugates. Nature Biotechnology |
Jahns H, Degaonkar R, Podbevsek P, et al. (2021) Small circular interfering RNAs (sciRNAs) as a potent therapeutic platform for gene-silencing. Nucleic Acids Research |
Klein D, Goldberg S, Theile CS, et al. (2021) Centyrin Ligands for Extrahepatic Delivery of siRNA. Molecular Therapy : the Journal of the American Society of Gene Therapy |
Brown CR, Gupta S, Qin J, et al. (2020) Investigating the pharmacodynamic durability of GalNAc-siRNA conjugates. Nucleic Acids Research |
Kumar P, Parmar RG, Brown CR, et al. (2019) 5'-Morpholino modification of the sense strand of an siRNA makes it a more effective passenger. Chemical Communications (Cambridge, England) |
Janas MM, Zlatev I, Liu J, et al. (2019) Safety evaluation of 2'-deoxy-2'-fluoro nucleotides in GalNAc-siRNA conjugates. Nucleic Acids Research |
Zewge D, Butora G, Sherer EC, et al. (2018) Post-Synthetic Modification of Oligonucleotides via Orthogonal Amidation and Copper Catalyzed Cycloaddition Reactions. Bioconjugate Chemistry |