David E. Metzler

Affiliations: 
Biochemistry Iowa State University, Ames, IA, United States 
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"David E. Metzler"
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Parents

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Esmond E. Snell grad student 1952 UW Madison
 (Transamination and other reactions of vitamin B₆)

Children

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Robert V. Stevens research assistant 1963 Iowa State
Ralph G. Yount grad student 1958 Iowa State
Pill-Soon Song post-doc 1964-1965 Iowa State
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Publications

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Metzler DE. (1997) Nuclear magnetic resonance in study of active sites of pyridoxal-dependent enzymes. Methods in Enzymology. 280: 30-40
Mollova ET, Metzler DE, Kintanar A, et al. (1997) Use of 1H-15N heteronuclear multiple-quantum coherence NMR spectroscopy to study the active site of aspartate aminotransferase. Biochemistry. 36: 615-25
Chu WC, Metzler DE. (1994) Enzymatically active truncated cat brain glutamate decarboxylase: expression, purification, and absorption spectrum. Archives of Biochemistry and Biophysics. 313: 287-95
Firsov LM, Neustroev KN, Aleshin AE, et al. (1994) NMR spectroscopy of exchangeable protons of glucoamylase and of complexes with inhibitors in the 9-15-ppm range. European Journal of Biochemistry / Febs. 223: 293-302
Yano T, Hinoue Y, Chen VJ, et al. (1993) Role of an active site residue analyzed by combination of mutagenesis and coenzyme analog. Journal of Molecular Biology. 234: 1218-29
Metzler CM, Metzler DE, Kintanar A, et al. (1991) NMR spectra of exchangeable protons of pyridoxal phosphate-dependent enzymes. Biochemical and Biophysical Research Communications. 178: 385-92
Metzler CM, Viswanath R, Metzler DE. (1991) Equilibria and absorption spectra of tryptophanase. The Journal of Biological Chemistry. 266: 9374-81
Kraus GA, Kim H, Thomas PJ, et al. (1990) Analogs of Glutamic Acid: Synthesis and Biological Evaluation Synthetic Communications. 20: 2667-2673
Miura R, Metzler CM, Metzler DE. (1989) Reactions of phosphonate analogs of pyridoxal phosphate with apo-aspartate aminotransferase. Archives of Biochemistry and Biophysics. 270: 526-40
Metzler CM, Mitra J, Metzler DE, et al. (1988) Correlation of polarized absorption spectroscopic and X-ray diffraction studies of crystalline cytosolic aspartate aminotransferase of pig hearts. Journal of Molecular Biology. 203: 197-220
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