Smaïl Khelili

Affiliations: 
University Paris 11 
Area:
KATP channels, Cromakalim, Aminoacide, Muscle relaxant activity, Β amyloid peptide, Alzheimer's disease, Azatide, Fluorinated and hydroxylated peptidomimetics, Dimerization, Β sheet
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"Smaïl Khelili"
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Stiti MZ, Belghobsi M, Habila T, et al. (2020) Synthesis and vasodilator activity of new 1,4-dihyropyridines bearing sulfonylurea, urea and thiourea moieties Chemical Papers. 74: 915-928
Harrouche K, Lahouel A, Belghobsi M, et al. (2019) Synthesis, characterization, and investigation of the antioxidant activity of some 1,2,4-benzothiadiazine-1,1-dioxides bearing sulfonylthioureas moieties Canadian Journal of Chemistry. 97: 824-832
Habila T, Belghobsi M, Stiti M, et al. (2019) Synthesis and vasodilator activity of 3,4-dihydropyrimidin-2(1H)-ones bearing urea, thiourea, and sulfonylurea moieties Canadian Journal of Chemistry. 97: 20-28
Bouhedja M, Peres B, Fhayli W, et al. (2017) Design, synthesis and biological evaluation of novel ring-opened cromakalim analogues with relaxant effects on vascular and respiratory smooth muscles and as stimulators of elastin synthesis. European Journal of Medicinal Chemistry. 144: 774-796
Harrouche K, Renard JF, Bouider N, et al. (2016) Synthesis, characterization and biological evaluation of benzothiazoles and tetrahydrobenzothiazoles bearing urea or thiourea moieties as vasorelaxants and inhibitors of the insulin releasing process. European Journal of Medicinal Chemistry. 115: 352-60
Bouider N, Fhayli W, Ghandour Z, et al. (2015) Design and synthesis of new potassium channel activators derived from the ring opening of diazoxide: study of their vasodilatory effect, stimulation of elastin synthesis and inhibitory effect on insulin release. Bioorganic & Medicinal Chemistry. 23: 1735-46
Akika F, Kihal N, Habila T, et al. (2013) Synthesis and Characterization of Zn(1-x)NixAl2O4 Spinels as a New Heterogeneous Catalyst of Biginelli's Reaction Bulletin of the Korean Chemical Society. 34: 1445-1453
Khelili S, Kihal N, Yekhlef M, et al. (2012) Synthesis and pharmacological activity of N-(2,2-dimethyl-3,4-dihydro-2H-1-benzopyran-4-yl)-4H-1,2,4-benzothiadiazine-3-carboxamides 1,1-dioxides on rat uterus, rat aorta and rat pancreatic β-cells. European Journal of Medicinal Chemistry. 54: 873-8
Khelili S, Florence X, Bouhadja M, et al. (2008) Synthesis and activity on rat aorta rings and rat pancreatic beta-cells of ring-opened analogues of benzopyran-type potassium channel activators. Bioorganic & Medicinal Chemistry. 16: 6124-30
Khelili S, Lebrun P, de Tullio P, et al. (2006) Synthesis and pharmacological evaluation of some N-arylsulfonyl-N-methyl-N'-(2,2-dimethyl-2H-1-benzopyran-4-yl)ureas structurally related to cromakalim. Bioorganic & Medicinal Chemistry. 14: 3530-4
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