Grégory Chaume
Affiliations: | Université de Cergy-Pontoise |
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Parents
Sign in to add mentorJanick Ardisson | grad student | 2003 | Université de Cergy-Pontoise | |
(Vers la synthèse totale de la griséoviridine, antibiotique de type streptogramine) |
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Publications
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Sanchez CA, Gadais C, Chaume G, et al. (2020) Enantiopure 5-CF-Proline: Synthesis, Incorporation in Peptides, and Tuning of the Peptide Bond Geometry. Organic Letters |
Gadais C, Van Holsbeeck K, Moors S, et al. (2019) Trifluoromethylated proline surrogates as part of "Pro-Pro" turn-inducing templates. Chembiochem : a European Journal of Chemical Biology |
Oliver M, Gadais C, García-Pindado J, et al. (2018) Trifluoromethylated proline analogues as efficient tools to enhance the hydrophobicity and to promote passive diffusion transport of the L-prolyl-L-leucyl glycinamide (PLG) tripeptide Rsc Advances. 8: 14597-14602 |
Chaume G, Simon J, Lensen N, et al. (2017) Homochiral versus Heterochiral Trifluoromethylated Pseudoproline Containing Dipeptides: A Powerful Tool to Switch the Prolyl-Amide Bond Conformation. The Journal of Organic Chemistry |
Simon J, Pytkowicz J, Lensen N, et al. (2016) Incorporation of Trifluoromethylated Proline and Surrogates into Peptides: Application to the Synthesis of Fluorinated Analogues of the Neuroprotective Glycine-Proline-Glutamate (GPE) Tripeptide. The Journal of Organic Chemistry |
Lubin H, Pytkowicz J, Chaume G, et al. (2015) Synthesis of enantiopure trans-2,5-disubstituted trifluoromethylpyrrolidines and (2S,5R)-5-trifluoromethylproline. The Journal of Organic Chemistry. 80: 2700-8 |
Chaume G, Simon J, Caupène C, et al. (2013) Incorporation of CF3-pseudoprolines into peptides: a methodological study. The Journal of Organic Chemistry. 78: 10144-53 |
Jlalia I, Lensen N, Chaume G, et al. (2013) Synthesis of an MIF-1 analogue containing enantiopure (S)-α-trifluoromethyl-proline and biological evaluation on nociception. European Journal of Medicinal Chemistry. 62: 122-9 |
Chaume G, Feytens D, Chassaing G, et al. (2013) Conformational properties of peptides incorporating a fluorinated pseudoproline residue New Journal of Chemistry. 37: 1336-1342 |
Feytens D, Chaume G, Chassaing G, et al. (2012) Local control of the cis-trans isomerization and backbone dihedral angles in peptides using trifluoromethylated pseudoprolines. The Journal of Physical Chemistry. B. 116: 4069-79 |