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Zucai Suo

Affiliations: 
Chemistry and Biochemistry Ohio State University, Columbus, Columbus, OH 
Area:
enzymes involved in DNA/RNA replication, Hepatitis C replication, drug design
Website:
http://chemistry.osu.edu/faculty/suo
Google:
"Zucai Suo"
Bio:

http://chemistry.osu.edu/~suo.3
http://chemistry.gsu.edu/faculty/Huang/Zucai_Suo,%202009-5.pdf

Mean distance: 7.34
 
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Publications

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Stephenson AA, Cao S, Taggart DJ, et al. (2021) Design, synthesis, and evaluation of liver-specific gemcitabine prodrugs for potential treatment of hepatitis C virus infection and hepatocellular carcinoma. European Journal of Medicinal Chemistry. 213: 113135
Raper AT, Maxwell BA, Suo Z. (2021) Dynamic processing of a common oxidative DNA lesion by the first two enzymes of the base excision repair pathway. Journal of Molecular Biology. 166811
Zahurancik WJ, Suo Z. (2020) Kinetic investigation of the polymerase and exonuclease activities of human DNA polymerase ε holoenzyme. The Journal of Biological Chemistry. 295: 17251-17264
Chu X, Suo Z, Wang J. (2020) Investigating the trade-off between folding and function in a multidomain Y-family DNA polymerase. Elife. 9
Zahurancik WJ, Suo Z. (2020) Kinetic investigation of the polymerase and exonuclease activities of human DNA polymerase epsilon holoenzyme. The Journal of Biological Chemistry
Galati MA, Hodel KP, Gams MS, et al. (2020) Cancers from novel Pole mutant mouse models provide insights into polymerase-mediated hypermutagenesis and immune checkpoint blockade. Cancer Research
Hodel KP, Sun MJS, Ungerleider N, et al. (2020) POLE Mutation Spectra Are Shaped by the Mutant Allele Identity, Its Abundance, and Mismatch Repair Status. Molecular Cell
Chu WT, Suo Z, Wang J. (2020) Binding-Induced Conformational Changes Involved in Sliding Clamp PCNA and DNA Polymerase DPO4. Iscience. 23: 101117
Chu X, Suo Z, Wang J. (2020) Confinement and Crowding Effects on Folding of a Multi-domain Y-family DNA Polymerase. Journal of Chemical Theory and Computation
Hung M, Tokarsky EJ, Lagpacan L, et al. (2019) Elucidating molecular interactions of L-nucleotides with HIV-1 reverse transcriptase and mechanism of M184V-caused drug resistance. Communications Biology. 2: 469
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