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Gerard D. Wright

Affiliations:

Biochemistry

McMaster University, Hamilton, ON, Canada

Area:

Antibiotic resistance; chemically synthesizing antibiotics

Website:

http://fhs.mcmaster.ca/main/canada_chairs/molecular_studies_antibiotics_chair.html

Google:

"Gerard D. Wright"

Bio:

http://iidrlabs.csu.mcmaster.ca/wrightwiki/wrightlab/?page_id=310
http://fhs.mcmaster.ca/biochem/wright_gerald.html

Mean distance: 7.32

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Parents

John F. Honek	grad student	1990	University of Waterloo
(Investigation of the lanosterol 14α-demethylase (P-450₁₄DM) from Saccharomyces cerevisiae)
Christopher T. Walsh	post-doc	1991-1995	Harvard Medical School

Children

Paul R. Thompson	grad student	1994-2000	McMaster University
David C. Bareich	grad student	2003	McMaster University
Denis M. Daigle	grad student	2003	McMaster University
David D. Boehr	grad student	2004	McMaster University
Kari-Ann Draker	grad student	2004	McMaster University
Jarrod W Johnson	post-doc	2015-2017	McMaster University

Collaborators

BETA: Related publications

Publications

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Cook MA, Pallant D, Ejim L, et al. (2023) Lessons from assembling a microbial natural product and pre-fractionated extract library in an academic laboratory. Journal of Industrial Microbiology & Biotechnology
Schaenzer AJ, Rodriguez Hernandez A, Tsai K, et al. (2023) Angucyclinones rescue PhLOPS antibiotic activity by inhibiting Cfr-dependent antibiotic resistance. Mbio. 14: e0179123
Bordeleau E, Stogios PJ, Evdokimova E, et al. (2023) Mechanistic plasticity in ApmA enables aminoglycoside promiscuity for resistance. Nature Chemical Biology. 20: 234-242
Gómez-Arrebola C, Hernandez SB, Culp EJ, et al. (2023) susceptibility to complestatin and corbomycin depends on the VraSR two-component system. Microbiology Spectrum. 11: e0037023
Koteva K, Xu M, Wang W, et al. (2023) Synthetic Biology Facilitates Semisynthetic Development of Type V Glycopeptide Antibiotics Targeting Vancomycin-Resistant . Journal of Medicinal Chemistry
Surette MD, Waglechner N, Koteva K, et al. (2022) HelR is a helicase-like protein that protects RNA polymerase from rifamycin antibiotics. Molecular Cell
Stogios PJ, Bordeleau E, Xu Z, et al. (2022) Structural and molecular rationale for the diversification of resistance mediated by the Antibiotic_NAT family. Communications Biology. 5: 263
Xu M, Wang W, Wright GD. (2021) Glycopeptide antibiotic discovery in the genomic era. Methods in Enzymology. 665: 325-346
Privalsky TM, Soohoo AM, Wang J, et al. (2021) Prospects for Antibacterial Discovery and Development. Journal of the American Chemical Society. 143: 21127-21142
Alder A, Struck NS, Xu M, et al. (2021) A non-reactive natural product precursor of the duocarmycin family has potent and selective antimalarial activity. Cell Chemical Biology

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