Karen N. Allen, Ph.D

1991- Chemistry Boston University, Boston, MA, United States 
protein crystallography, enzymology, structural homology
"Karen Allen"
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O'Toole KH, Bernstein HM, Allen KN, et al. (2021) The surprising structural and mechanistic dichotomy of membrane-associated phosphoglycosyl transferases. Biochemical Society Transactions
O'Toole KH, Imperiali B, Allen KN. (2021) Glycoconjugate pathway connections revealed by sequence similarity network analysis of the monotopic phosphoglycosyl transferases. Proceedings of the National Academy of Sciences of the United States of America. 118
Harvey C, O'Toole K, Liu C, et al. (2020) Structural Analysis of Binding Determinants of Trehalose-6-phosphate Phosphatase using Ground-State Complexes. Biochemistry
Victor T, O'Toole K, Easthon LM, et al. (2020) Lanthanide-Binding Tags for 3D X-Ray Imaging of Proteins in Cells at Nanoscale Resolution. Journal of the American Chemical Society
Zhong M, Lynch AJ, Muellers SN, et al. (2019) Interaction Energetics and Druggability of the Protein-Protein Interaction between Kelch-like ECH-associated Protein 1 (KEAP1) and Nuclear Factor, Erythroid 2 Like 2 (Nrf2). Biochemistry
Allen KN, Imperiali B. (2019) Structural and mechanistic themes in glycoconjugate biosynthesis at membrane interfaces. Current Opinion in Structural Biology. 59: 81-90
Allen KN, Entova S, Ray LC, et al. (2018) Monotopic Membrane Proteins Join the Fold. Trends in Biochemical Sciences
Victor TW, Easthon LM, Ge M, et al. (2018) X-ray Fluorescence Nanotomography of Single Bacteria with a Sub-15 nm Beam. Scientific Reports. 8: 13415
Harvey CM, O'Toole KH, Allen KN. (2018) Crystallization of Liganded Phosphatases in the HAD Superfamily. Methods in Enzymology. 607: 157-184
Zhang C, Allen KN, Dunaway-Mariano D. (2018) Mechanism of Substrate Recognition and Catalysis of the Haloalkanoic Acid Dehalogenase Family Member, α-Phosphoglucomutase. Biochemistry
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