Karen N. Allen, Ph.D

1991- Chemistry Boston University, Boston, MA, United States 
protein crystallography, enzymology, structural homology
"Karen Allen"
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Muellers SN, Nyitray MM, Reynarowych N, et al. (2022) Structure-Guided Insight into the Specificity and Mechanism of a Parasitic Nucleoside Hydrolase. Biochemistry
Turner LD, Nielsen AL, Lin L, et al. (2021) Use of Crystallography and Molecular Modeling for the Inhibition of the Botulinum Neurotoxin A Protease. Acs Medicinal Chemistry Letters. 12: 1318-1324
O'Toole KH, Bernstein HM, Allen KN, et al. (2021) The surprising structural and mechanistic dichotomy of membrane-associated phosphoglycosyl transferases. Biochemical Society Transactions
O'Toole KH, Imperiali B, Allen KN. (2021) Glycoconjugate pathway connections revealed by sequence similarity network analysis of the monotopic phosphoglycosyl transferases. Proceedings of the National Academy of Sciences of the United States of America. 118
Lin L, Olson ME, Sugane T, et al. (2020) A Catch and Anchor Approach to Combat both Toxicity and Longevity of Botulinum Toxin A. Journal of Medicinal Chemistry
Harvey C, O'Toole K, Liu C, et al. (2020) Structural Analysis of Binding Determinants of Trehalose-6-phosphate Phosphatase using Ground-State Complexes. Biochemistry
Tararina MA, Allen KN. (2020) Bioinformatic Analysis of the Flavin-Dependent Amine Oxidase Superfamily: Adaptations for Substrate Specificity and Catalytic Diversity. Journal of Molecular Biology
Victor T, O'Toole K, Easthon LM, et al. (2020) Lanthanide-Binding Tags for 3D X-Ray Imaging of Proteins in Cells at Nanoscale Resolution. Journal of the American Chemical Society
Pyeatt G, Muellers S, Whitty A, et al. (2020) Structural Characterization of the Covalent Binding of Keap1 and Thiol‐containing Small Molecules The Faseb Journal. 34: 1-1
Dodge G, O’Toole K, Bernstein H, et al. (2020) Structural and Functional Characterization of Phosphoglycosyl Transferases from Human Pathogens The Faseb Journal. 34: 1-1
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