Leslie Hough

Chemistry King's College London, London, UK 
carbohydrate chemistry
"Leslie Hough"

Leslie Hough was born in 1925 in Lancashire. He graduated in 1946 from the University of Manchester with an Honors degree in Chemistry. He commenced research on carbohydrates with Professor (later Sir Edmund) E. L. Hirst and Dr. (later Professor) J.K.N. Jones, took the M.Sc. in 1947 and completed his Ph.D. in 1949. Collaboration with Jones continued when Dr. Hough joined the academic staff at the University of Bristol in 1950. As a Fulbright Scholar he took sabbatical leave in 1952 to study at Purdue University with Professor Roy L. Whistler. When J.K.N. Jones became the Chown Research Professor at Queens University, Ontario, in 1954, Dr. Hough directed the carbohydrate research at Bristol on glycoproteins, carbon-14 tracer studies and the interplay between conformation and reactivity. Research on sucrose commenced in 1956 with the support of the International Sugar Research Foundation (now W.R.S.O.) and continued with Tate and Lyle.
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Gao S, Stone RA, Hough LJ, et al. (2016) Physical activity counseling in overweight and obese primary care patients: Outcomes of the VA-STRIDE randomized controlled trial. Preventive Medicine Reports. 3: 113-20
Sevick MA, Piraino BM, St-Jules DE, et al. (2016) No Difference in Average Interdialytic Weight Gain Observed in a Randomized Trial With a Technology-Supported Behavioral Intervention to Reduce Dietary Sodium Intake in Adults Undergoing Maintenance Hemodialysis in the United States: Primary Outcomes of the BalanceWise Study Journal of Renal Nutrition
Hough LH, Segal S. (2016) Effects of developmental hyperserotonemia on the morphology of rat dentate nuclear neurons Neuroscience. 322: 178-194
Kuan HS, Blackwell R, Hough LE, et al. (2015) Hysteresis, reentrance, and glassy dynamics in systems of self-propelled rods. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 92: 060501
Diroll BT, Weigandt KM, Jishkariani D, et al. (2015) Quantifying "Softness" of Organic Coatings on Gold Nanoparticles Using Correlated Small-Angle X-ray and Neutron Scattering. Nano Letters
Hough LE, Dutta K, Sparks S, et al. (2015) The molecular mechanism of nuclear transport revealed by atomic-scale measurements. Elife. 4
Jishkariani D, Diroll BT, Cargnello M, et al. (2015) Dendron-Mediated Engineering of Interparticle Separation and Self-Assembly in Dendronized Gold Nanoparticles Superlattices. Journal of the American Chemical Society
Hough LB, Nalwalk JW, Ding X, et al. (2015) Opioid Analgesia in P450 Gene Cluster Knockout Mice: A Search for Analgesia-Relevant Isoforms. Drug Metabolism and Disposition: the Biological Fate of Chemicals
Hakhverdyan Z, Domanski M, Hough LE, et al. (2015) Rapid, optimized interactomic screening. Nature Methods. 12: 553-60
Hough LB, Nalwalk JW, Yang W, et al. (2015) Neuronal cytochrome P450 activity and opioid analgesia: relevant sites and mechanisms. Brain Research. 1616: 10-8
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