Sharon Swanger, PhD

Affiliations: 
Emory University, Atlanta, GA 
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"Sharon Swanger"
Mean distance: 15.15 (cluster 11)
 
SNBCP
Cross-listing: Neurotree

Parents

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Itzhak Fischer research assistant 2002-2005 (Neurotree)
Gary J. Bassell grad student Emory
Stephen F. Traynelis post-doc Emory (Neurotree)
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Publications

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Perszyk RE, Swanger SA, Shelley C, et al. (2020) Biased modulators of NMDA receptors control channel opening and ion selectivity. Nature Chemical Biology
Li J, Zhang J, Tang W, et al. (2019) De Novo GRIN Variants in NMDA Receptor M2 Channel Pore-Forming Loop Are Associated with Neurological Diseases. Human Mutation
Hanson E, Armbruster M, Lau LA, et al. (2019) Tonic activation of GluN2C/GluN2D-containing NMDA receptors by ambient glutamate facilitates cortical interneuron maturation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience
Bhattacharya S, Khatri A, Swanger SA, et al. (2018) Triheteromeric GluN1/GluN2A/GluN2C NMDARs with Unique Single-Channel Properties Are the Dominant Receptor Population in Cerebellar Granule Cells. Neuron. 99: 315-328.e5
Fry AE, Fawcett KA, Zelnik N, et al. (2018) De novo mutations in GRIN1 cause extensive bilateral polymicrogyria. Brain : a Journal of Neurology
Swanger SA, Vance KM, Acker TM, et al. (2017) A novel negative allosteric modulator selective for GluN2C/2D-containing NMDA receptors inhibits synaptic transmission in hippocampal interneurons. Acs Chemical Neuroscience
Chen W, Shieh C, Swanger SA, et al. (2017) GRIN1 mutation associated with intellectual disability alters NMDA receptor trafficking and function. Journal of Human Genetics
Ogden KK, Chen W, Swanger SA, et al. (2017) Molecular Mechanism of Disease-Associated Mutations in the Pre-M1 Helix of NMDA Receptors and Potential Rescue Pharmacology. Plos Genetics. 13: e1006536
Keen JR, Swanger SA, Traynelis SF, et al. (2016) The role of glutamate transport and SLC7A11 expression in tumor-associate seizures and survival in patients with malignant gliomas. Annals of Translational Medicine. 4: S18
Swanger SA, Chen W, Wells G, et al. (2016) Mechanistic Insight into NMDA Receptor Dysregulation by Rare Variants in the GluN2A and GluN2B Agonist Binding Domains. American Journal of Human Genetics
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