Sunil Kumar Talapatra

Calcutta University 
"Sunil Kumar Talapatra"


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Asima Chatterjee grad student 1957 University of Calcutta
 (Ph.D: "Studies on the active principles of some apocynaceous plants")
Michael P. Cava post-doc Ohio State
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Talapatra SK, Rath O, Clayton E, et al. (2016) Depsidones from Lichens as Natural Product Inhibitors of M-Phase Phosphoprotein 1, a Human Kinesin Required for Cytokinesis. Journal of Natural Products
Labrière C, Talapatra SK, Thoret S, et al. (2015) New MKLP-2 inhibitors in the paprotrain series: Design, synthesis and biological evaluations. Bioorganic & Medicinal Chemistry
Talapatra SK, Harker B, Welburn JP. (2015) The C-terminal region of the motor protein MCAK controls its structure and activity through a conformational switch. Elife. 4
Klejnot M, Gabrielsen M, Cameron J, et al. (2013) Analysis of the human cofilin 1 structure reveals conformational changes required for actin binding. Acta Crystallographica. Section D, Biological Crystallography. 69: 1780-8
Talapatra SK, Anthony NG, Mackay SP, et al. (2013) Mitotic kinesin Eg5 overcomes inhibition to the phase I/II clinical candidate SB743921 by an allosteric resistance mechanism. Journal of Medicinal Chemistry. 56: 6317-29
Good JA, Wang F, Rath O, et al. (2013) Optimized S-trityl-L-cysteine-based inhibitors of kinesin spindle protein with potent in vivo antitumor activity in lung cancer xenograft models. Journal of Medicinal Chemistry. 56: 1878-93
Ulaganathan V, Talapatra SK, Rath O, et al. (2013) Structural insights into a unique inhibitor binding pocket in kinesin spindle protein. Journal of the American Chemical Society. 135: 2263-72
Talapatra SK, Schüttelkopf AW, Kozielski F. (2012) The structure of the ternary Eg5-ADP-ispinesib complex. Acta Crystallographica. Section D, Biological Crystallography. 68: 1311-9
Putey A, Popowycz F, Do QT, et al. (2009) Indolobenzazepin-7-ones and 6-, 8-, and 9-membered ring derivatives as tubulin polymerization inhibitors: synthesis and structure--activity relationship studies. Journal of Medicinal Chemistry. 52: 5916-25
Das AK, Datta M, Mazumdar SK, et al. (1993) Crystal and molecular structure of α-(9-adeninylmethyl) butyrolactone Journal of Crystallographic and Spectroscopic Research. 23: 247-249
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