Kang Le

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1995 Chemistry University of Missouri-Rolla, Rolla, MO, United States 
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Ma J, Goodwani S, Acton PJ, et al. (2021) Inhibition of dual leucine zipper kinase prevents chemotherapy-induced peripheral neuropathy and cognitive impairments. Pain
Le K, Wellik LE, Maurer MJ, et al. (2021) JAK2 activation promotes tumorigenesis in ALK-negative anaplastic large cell lymphoma via regulating oncogenic STAT1-PVT1 lncRNA axis. Blood Cancer Journal. 11: 56
Soth MJ, Le K, Di Francesco ME, et al. (2020) Discovery of IPN60090, a Clinical Stage Selective Glutaminase-1 (GLS-1) Inhibitor with Excellent Pharmacokinetic and Physicochemical Properties. Journal of Medicinal Chemistry
Goodwani S, Fernandez C, Acton PJ, et al. (2020) Dual Leucine Zipper Kinase Is Constitutively Active in the Adult Mouse Brain and Has Both Stress-Induced and Homeostatic Functions. International Journal of Molecular Sciences. 21
Le K, Matar H, Gupta M. (2020) Bromodomain epigenetic protein promotes metastatic potential in melanoma cells via increased invasiveness and decreased macrophage-mediated phagocytosis. The Journal of Investigative Dermatology
Le K, Steagall WK, Stylianou M, et al. (2018) Effect of beta-agonists on LAM progression and treatment. Proceedings of the National Academy of Sciences of the United States of America
Li CC, Le K, Kato J, et al. (2016) Enhancement of β-catenin activity by BIG1 plus BIG2 via Arf activation and cAMP signals. Proceedings of the National Academy of Sciences of the United States of America
Chen PW, Jian X, Heissler SM, et al. (2016) The Arf GTPase-activating protein, ASAP1, Binds Nonmuscle Myosin 2A to Control Remodeling of the Actomyosin Network. The Journal of Biological Chemistry
Li C, Chen S, Yu Y, et al. (2014) BIG1, a brefeldin A-inhibited guanine nucleotide-exchange factor, is required for GABA-gated Cl⁻ influx through regulation of GABAA receptor trafficking. Molecular Neurobiology. 49: 808-19
Kester RF, Donnell AF, Lou Y, et al. (2013) Optimization of benzodiazepinones as selective inhibitors of the X-linked inhibitor of apoptosis protein (XIAP) second baculovirus IAP repeat (BIR2) domain. Journal of Medicinal Chemistry. 56: 7788-803
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