Joerg Langowski, Dr. rer. nat.

Affiliations: 
Biophysics of Macromolecules German Cancer Research Center, Heidelberg, Baden-Württemberg, Germany 
Area:
Biophysics, single molecule spectroscopy, computational biology
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"Joerg Langowski"
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SNBCP
Cross-listing: Computational Biology Tree

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Publications

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Lehmann K, Felekyan S, Kühnemuth R, et al. (2020) Dynamics of the nucleosomal histone H3 N-terminal tail revealed by high precision single-molecule FRET. Nucleic Acids Research
Gansen A, Felekyan S, Kühnemuth R, et al. (2018) High precision FRET studies reveal reversible transitions in nucleosomes between microseconds and minutes. Nature Communications. 9: 4628
Rubio-Cosials A, Battistini F, Gansen A, et al. (2017) Protein Flexibility and Synergy of HMG Domains Underlie U-Turn Bending of DNA by TFAM in Solution. Biophysical Journal
Langowski J. (2017) Single plane illumination microscopy as a tool for studying nucleome dynamics. Methods (San Diego, Calif.). 123: 3-10
Sauer PV, Timm J, Liu D, et al. (2017) Insights into the molecular architecture and histone H3-H4 deposition mechanism of yeast Chromatin assembly factor 1. Elife. 6
Hazan NP, Tomov TE, Tsukanov R, et al. (2015) Nucleosome Core Particle Disassembly and Assembly Kinetics Studied Using Single-Molecule Fluorescence. Biophysical Journal. 109: 1676-85
Elbel T, Langowski J. (2015) The effect of DNA supercoiling on nucleosome structure and stability. Journal of Physics. Condensed Matter : An Institute of Physics Journal. 27: 064105
Erler J, Zhang R, Petridis L, et al. (2014) The role of histone tails in the nucleosome: a computational study. Biophysical Journal. 107: 2911-22
Hieb AR, Gansen A, Böhm V, et al. (2014) The conformational state of the nucleosome entry-exit site modulates TATA box-specific TBP binding Nucleic Acids Research. 42: 7561-7576
Brazda P, Krieger J, Daniel B, et al. (2014) Ligand binding shifts highly mobile retinoid X receptor to the chromatin-bound state in a coactivator-dependent manner, as revealed by single-cell imaging. Molecular and Cellular Biology. 34: 1234-45
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