Daniel J. Sprague, M.D., Ph.D.

Affiliations: 
Cell Biology, Neurobiology, and Anatomy Medical College of Wisconsin 
Area:
Synthetic Chemistry
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"Daniel Sprague"
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Publications

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Park SK, Sprague DJ, Rohr CM, et al. (2023) The anthelmintic meclonazepam activates a schistosome transient receptor potential channel. The Journal of Biological Chemistry. 300: 105528
Sprague DJ, Kaethner M, Park SK, et al. (2023) The Anthelmintic Activity of Praziquantel Analogs Correlates with Structure-Activity Relationships at TRPM Orthologs. Acs Medicinal Chemistry Letters. 14: 1537-1543
Sprague DJ, Park SK, Gramberg S, et al. (2023) Target-based discovery of a broad spectrum flukicide. Biorxiv : the Preprint Server For Biology
Malcolm NJ, Palkovic B, Sprague DJ, et al. (2023) Mu-opioid receptor selective superagonists produce prolonged respiratory depression. Iscience. 26: 107121
Yahya NA, Lanham JK, Sprague DJ, et al. (2023) Molecular and cellular basis of praziquantel action in the cardiovascular system. American Journal of Physiology. Cell Physiology
Rohr CM, Sprague DJ, Park SK, et al. (2022) Natural variation in the binding pocket of a parasitic flatworm TRPM channel resolves the basis for praziquantel sensitivity. Proceedings of the National Academy of Sciences of the United States of America. 120: e2217732120
AbuEid M, Keyes RF, McAllister D, et al. (2022) Fluorinated triphenylphosphonium analogs improve cell selectivity and detection of mito-metformin. Iscience. 25: 105670
Gunaratne GS, Rebbeck RT, McGurran LM, et al. (2021) Identification of a dihydropyridine scaffold that blocks ryanodine receptors. Iscience. 25: 103706
Sprague DJ, Getschman AE, Fenske TG, et al. (2021) Trisubstituted 1,3,5-Triazines: The First Ligands of the sY12-Binding Pocket on Chemokine CXCL12. Acs Medicinal Chemistry Letters. 12: 1773-1782
Sprague DJ, Johnston JN. (2020) Substituted Imidazoline Synthesis: A Diastereo- and Enantioselective aza-Henry Route to a Human Proteasome Modulator. Organic Letters
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