Rajendra P. Tanpure, Ph.D.

Affiliations: 
2003 Baylor University, Waco, TX 
Area:
Organic Chemistry
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"Rajendra Tanpure"
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Kevin George Pinney grad student 2003 Baylor University
 (New synthetic methodology for the stereoselective preparation of functionalized conjugated dienes from alkynyl oxirane precursors: Synthesis and biological evaluation of functionalized triarylalkenes as tubulin binding agents.)
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Publications

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Liu L, Schuetze R, Gerberich JL, et al. (2022) Demonstrating Tumor Vascular Disrupting Activity of the Small-Molecule Dihydronaphthalene Tubulin-Binding Agent OXi6196 as a Potential Therapeutic for Cancer Treatment. Cancers. 14
Guo Y, Wang H, Gerberich JL, et al. (2021) Imaging-Guided Evaluation of the Novel Small-Molecule Benzosuberene Tubulin-Binding Agent KGP265 as a Potential Therapeutic Agent for Cancer Treatment. Cancers. 13
Herdman CA, Strecker TE, Tanpure RP, et al. (2016) Synthesis and Biological Evaluation of Benzocyclooctene-based and Indene-based Anticancer Agents that Function as Inhibitors of Tubulin Polymerization. Medchemcomm. 7: 2418-2427
Herdman CA, Devkota L, Lin CM, et al. (2015) Structural interrogation of benzosuberene-based inhibitors of tubulin polymerization. Bioorganic & Medicinal Chemistry
Tanpure RP, Ren B, Peat TS, et al. (2015) Carbonic anhydrase inhibitors with dual-tail moieties to match the hydrophobic and hydrophilic halves of the carbonic anhydrase active site. Journal of Medicinal Chemistry. 58: 1494-501
Fisher GM, Tanpure RP, Douchez A, et al. (2014) Synthesis and evaluation of antimalarial properties of novel 4-aminoquinoline hybrid compounds. Chemical Biology & Drug Design. 84: 462-72
Tanpure RP, George CS, Strecker TE, et al. (2013) Synthesis of structurally diverse benzosuberene analogues and their biological evaluation as anti-cancer agents. Bioorganic & Medicinal Chemistry. 21: 8019-32
Tanpure RP, George CS, Sriram M, et al. (2012) An Amino-Benzosuberene Analogue That Inhibits Tubulin Assembly and Demonstrates Remarkable Cytotoxicity. Medchemcomm. 3: 720-724
Tanpure RP, Nguyen BL, Strecker TE, et al. (2011) Regioselective synthesis of water-soluble monophosphate derivatives of combretastatin A-1. Journal of Natural Products. 74: 1568-74
Tanpure RP, Strecker TE, Chaplin DJ, et al. (2010) Regio- and stereospecific synthesis of mono-beta-d-glucuronic acid derivatives of combretastatin A-1. Journal of Natural Products. 73: 1093-101
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