Rogelio Siles, Ph.D.

2006 Baylor University, Waco, TX 
Organic Chemistry, Pharmaceutical Chemistry
"Rogelio Siles"
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Kevin George Pinney grad student 2006 Baylor University
 (Design, synthesis, and biological evaluation of new anti-cancer nitrogen-containing combretastatins and novel cysteine protease inhibitors for the treatment of Chagas.)
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Shirali A, Sriram M, Hall JJ, et al. (2009) Development of synthetic methodology suitable for the radiosynthesis of combretastatin A-1 (CA1) and its corresponding prodrug CA1P. Journal of Natural Products. 72: 414-21
Siles R, Ackley JF, Hadimani MB, et al. (2008) Combretastatin dinitrogen-substituted stilbene analogues as tubulin-binding and vascular-disrupting agents. Journal of Natural Products. 71: 313-20
Trawick ML, Arispe‐Angulo WM, Chen S, et al. (2007) Kinetics of Thiosemicarbazone‐Based Inhibitors of Cathepsin L The Faseb Journal. 21
Siles R, Chen SE, Zhou M, et al. (2006) Design, synthesis, and biochemical evaluation of novel cruzain inhibitors with potential application in the treatment of Chagas' disease. Bioorganic & Medicinal Chemistry Letters. 16: 4405-9
Monk KA, Siles R, Hadimani MB, et al. (2006) Design, synthesis, and biological evaluation of combretastatin nitrogen-containing derivatives as inhibitors of tubulin assembly and vascular disrupting agents. Bioorganic & Medicinal Chemistry. 14: 3231-44
Monk KA, Siles R, Pinney KG, et al. (2003) Synthesis of 4-methoxy-3,5-dinitrobenzaldehyde: A correction to supposed tele nucleophilic aromatic substitution Tetrahedron Letters. 44: 3759-3761
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