Madhavi Sriram, Ph.D.

2007 Chemistry and Biochemistry Baylor University, Waco, TX 
Organic Chemistry
"Madhavi Sriram"
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Kevin George Pinney grad student 2007 Baylor University
 (Design, synthesis, biochemical and biological evaluation of benzocyclic and enediyne analogs of combretastatins as potential tubulin binding ligands in the treatment of cancer.)
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Maguire CJ, Chen Z, Mocharla VP, et al. (2018) Synthesis of dihydronaphthalene analogues inspired by combretastatin A-4 and their biological evaluation as anticancer agents. Medchemcomm. 9: 1649-1662
Tanpure RP, George CS, Strecker TE, et al. (2013) Synthesis of structurally diverse benzosuberene analogues and their biological evaluation as anti-cancer agents. Bioorganic & Medicinal Chemistry. 21: 8019-32
Hadimani MB, Macdonough MT, Ghatak A, et al. (2013) Synthesis of a 2-aryl-3-aroyl indole salt (OXi8007) resembling combretastatin A-4 with application as a vascular disrupting agent. Journal of Natural Products. 76: 1668-78
Tanpure RP, George CS, Sriram M, et al. (2012) An Amino-Benzosuberene Analogue That Inhibits Tubulin Assembly and Demonstrates Remarkable Cytotoxicity. Medchemcomm. 3: 720-724
Allen PH, Bloom AJ, Bragg R, et al. (2011) 19th international isotope society (UK group) symposium: synthesis & applications of labelled compounds 2010 Journal of Labelled Compounds and Radiopharmaceuticals. 54: 387-398
Shirali A, Sriram M, Hall JJ, et al. (2009) Development of synthetic methodology suitable for the radiosynthesis of combretastatin A-1 (CA1) and its corresponding prodrug CA1P. Journal of Natural Products. 72: 414-21
Brown RT, Murrell VL, McMordie A, et al. (2009) Carbon-14 radiosynthesis of combretastatin A-1 (CA1) and its corresponding phosphate prodrug (CA1P) Journal of Labelled Compounds and Radiopharmaceuticals. 52: 567-570
Sriram M, Hall JJ, Grohmann NC, et al. (2008) Design, synthesis and biological evaluation of dihydronaphthalene and benzosuberene analogs of the combretastatins as inhibitors of tubulin polymerization in cancer chemotherapy. Bioorganic & Medicinal Chemistry. 16: 8161-71
Hall JJ, Sriram M, Strecker TE, et al. (2008) Design, synthesis, biochemical, and biological evaluation of nitrogen-containing trifluoro structural modifications of combretastatin A-4. Bioorganic & Medicinal Chemistry Letters. 18: 5146-9
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