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John J. Hall

Affiliations: 
2008 Chemistry and Biochemistry Baylor University, Waco, TX 
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Kevin George Pinney grad student 2008 Baylor University
 (Inhibitors of tubulin, nitric oxide synthase, and HIF-1 alpha; synthesis, biological, and biochemical evaluation.)

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Hadimani MB, Macdonough MT, Ghatak A, et al. (2013) Synthesis of a 2-aryl-3-aroyl indole salt (OXi8007) resembling combretastatin A-4 with application as a vascular disrupting agent. Journal of Natural Products. 76: 1668-78
Macdonough MT, Strecker TE, Hamel E, et al. (2013) Synthesis and biological evaluation of indole-based, anti-cancer agents inspired by the vascular disrupting agent 2-(3'-hydroxy-4'-methoxyphenyl)-3-(3″,4″,5″-trimethoxybenzoyl)-6-methoxyindole (OXi8006). Bioorganic & Medicinal Chemistry. 21: 6831-43
Shirali A, Sriram M, Hall JJ, et al. (2009) Development of synthetic methodology suitable for the radiosynthesis of combretastatin A-1 (CA1) and its corresponding prodrug CA1P. Journal of Natural Products. 72: 414-21
Sriram M, Hall JJ, Grohmann NC, et al. (2008) Design, synthesis and biological evaluation of dihydronaphthalene and benzosuberene analogs of the combretastatins as inhibitors of tubulin polymerization in cancer chemotherapy. Bioorganic & Medicinal Chemistry. 16: 8161-71
Hall JJ, Sriram M, Strecker TE, et al. (2008) Design, synthesis, biochemical, and biological evaluation of nitrogen-containing trifluoro structural modifications of combretastatin A-4. Bioorganic & Medicinal Chemistry Letters. 18: 5146-9
Siles R, Ackley JF, Hadimani MB, et al. (2008) Combretastatin dinitrogen-substituted stilbene analogues as tubulin-binding and vascular-disrupting agents. Journal of Natural Products. 71: 313-20
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