Dennis W. Wolan
Affiliations: | Scripps Research Institute, La Jolla, La Jolla, CA, United States |
Area:
Chemical biology, structural biologyGoogle:
"Dennis Wolan"Mean distance: 9.07 | S | N | B | C | P |
Parents
Sign in to add mentor| Ian A. Wilson | grad student | 1999-2004 | Scripps Institute | |
| (Structural studies of the de novo purine biosynthesis enzyme ATIC and of the natural killer cell receptor NKG2D.) | ||||
| James A. Wells | post-doc | 2005-2010 | UCSF | |
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Publications
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| Chin EN, Yu C, Vartabedian VF, et al. (2020) Antitumor activity of a systemic STING-activating non-nucleotide cGAMP mimetic. Science (New York, N.Y.). 369: 993-999 |
| Yao Y, Kadam RU, Lee CD, et al. (2020) An influenza A hemagglutinin small-molecule fusion inhibitor identified by a new high-throughput fluorescence polarization screen. Proceedings of the National Academy of Sciences of the United States of America |
| Woehl JL, Kitamura S, Dillon N, et al. (2020) An irreversible inhibitor to probe the role of cysteine protease SpeB in evasion of host complement defenses. Acs Chemical Biology |
| Kok BP, Ghimire S, Kim W, et al. (2020) Discovery of small-molecule enzyme activators by activity-based protein profiling. Nature Chemical Biology |
| Kitamura S, Zheng Q, Woehl JL, et al. (2020) SuFEx-enabled high-throughput medicinal chemistry. Journal of the American Chemical Society |
| Smedley CJ, Li G, Barrow AS, et al. (2020) Diversity Oriented Clicking (DOC): Divergent Synthesis of SuFExable Pharmacophores From 2-Substituted-Alkynyl-1-Sulfonyl Fluoride (SASF) Hubs. Angewandte Chemie (International Ed. in English) |
| Xu JH, Eberhardt J, Hill-Payne B, et al. (2020) Integrative x-ray structure and molecular modeling for the rationalization of procaspase-8 inhibitor potency and selectivity. Acs Chemical Biology |
| Zheng Q, Woehl JL, Kitamura S, et al. (2019) SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase. Proceedings of the National Academy of Sciences of the United States of America |
| Gordon MH, Anowai A, Young D, et al. (2019) N-terminomics/TAILS profiling of proteases and their substrates in ulcerative colitis. Acs Chemical Biology |
| Thuy-Boun PS, Wolan DW. (2019) A glycal-based photoaffinity probe that enriches sialic acid binding proteins. Bioorganic & Medicinal Chemistry Letters |