Brian Cosgrove

Affiliations: 
Bioengineering and Orthopaedic Surgery University of Pennsylvania, Philadelphia, PA, United States 
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"Brian Cosgrove"
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Cosgrove BD, Bounds LR, Taylor CK, et al. (2024) Mechanosensitive genomic enhancers potentiate the cellular response to matrix stiffness. Biorxiv : the Preprint Server For Biology
Cosgrove BD, Loebel C, Driscoll TP, et al. (2021) Nuclear envelope wrinkling predicts mesenchymal progenitor cell mechano-response in 2D and 3D microenvironments. Biomaterials. 270: 120662
Haupt J, Stanley A, McLeod CM, et al. (2018) ACVR1 FOP mutation alters mechanosensing and tissue stiffness during heterotopic ossification. Molecular Biology of the Cell. mbcE18050311
Heo SJ, Cosgrove BD, Dai EN, et al. (2017) Mechano-Adaptation of the Stem Cell Nucleus. Nucleus (Austin, Tex.). 0
Loebel C, Szczesny SE, Cosgrove BD, et al. (2017) Crosslinking Chemistry of Tyramine-Modified Hyaluronan Hydrogels Alters Mesenchymal Stem Cell Early Attachment and Behavior. Biomacromolecules
Heo SJ, Han WM, Szczesny SE, et al. (2016) Mechanically Induced Chromatin Condensation Requires Cellular Contractility in Mesenchymal Stem Cells. Biophysical Journal. 111: 864-74
Cosgrove BD, Mui KL, Driscoll TP, et al. (2016) N-cadherin adhesive interactions modulate matrix mechanosensing and fate commitment of mesenchymal stem cells. Nature Materials
Caliari SR, Perepelyuk M, Cosgrove BD, et al. (2016) Stiffening hydrogels for investigating the dynamics of hepatic stellate cell mechanotransduction during myofibroblast activation. Scientific Reports. 6: 21387
Driscoll TP, Cosgrove BD, Heo SJ, et al. (2015) Cytoskeletal to Nuclear Strain Transfer Regulates YAP Signaling in Mesenchymal Stem Cells. Biophysical Journal. 108: 2783-93
Mohanraj B, Hou C, Meloni GR, et al. (2014) A high throughput mechanical screening device for cartilage tissue engineering. Journal of Biomechanics. 47: 2130-6
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